Nuzzi Giulia, Di Cicco Maria Elisa, Peroni Diego Giampietro
Section of Pediatrics, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Children (Basel). 2021 Apr 24;8(5):330. doi: 10.3390/children8050330.
Asthma and other allergic disorders, such as atopic dermatitis and food allergies, are common chronic health problems in childhood. The rapid rise in the prevalence of these conditions registered over the last few decades has stressed the need to identify the modifiable risk factors associated with the development of these diseases. Breast milk, recognized as the gold standard for healthy growth and development of the newborn, is one of the major factors associated with a lower incidence of allergic and infectious diseases in childhood and young adulthood. Although the underlying mechanisms for these effects are not well understood, breastfeeding leads to immune system maturation. In this narrative review, we summarize existing evidence on breastfeeding and human milk composition in relation to allergic disease prevention or development.
哮喘和其他过敏性疾病,如特应性皮炎和食物过敏,是儿童常见的慢性健康问题。过去几十年中这些疾病患病率的迅速上升凸显了识别与这些疾病发生相关的可改变风险因素的必要性。母乳被认为是新生儿健康生长发育的黄金标准,是与儿童期和青年期过敏性和感染性疾病发病率较低相关的主要因素之一。尽管这些作用的潜在机制尚不完全清楚,但母乳喂养可促进免疫系统成熟。在这篇叙述性综述中,我们总结了关于母乳喂养和母乳成分与过敏性疾病预防或发生相关的现有证据。