Mongioì Laura M, Perelli Sarah, Condorelli Rosita A, Barbagallo Federica, Crafa Andrea, Cannarella Rossella, La Vignera Sandro, Calogero Aldo E
Department of Clinical and Experimental Medicine, University of Catania, Via S. Sofia 78, 95123 Catania, Italy.
Molecules. 2021 Apr 24;26(9):2495. doi: 10.3390/molecules26092495.
Resveratrol (RSV) (3,4',5 trihydroxystilbene) is a natural non-flavonoid polyphenol widely present in the Mediterranean diet. In particular, RSV is found in grapes, peanuts, berries, and red wine. Many beneficial effects of this molecule on human health have been reported. In fact, it improves some clinical aspects of various diseases, such as obesity, tumors, hypertension, Alzheimer's disease, stroke, cardiovascular diseases, and diabetes mellitus. However, little is known about the relationship between this compound and male fertility and the few available results are often controversial. Therefore, this review evaluated the effects of RSV on human male fertility and the mechanisms through which this polyphenol could act on human spermatozoa.
白藜芦醇（RSV）（3,4',5-三羟基茋）是一种天然的非黄酮类多酚，广泛存在于地中海饮食中。特别是，RSV存在于葡萄、花生、浆果和红酒中。据报道，这种分子对人类健康有许多有益影响。事实上，它改善了各种疾病的一些临床症状，如肥胖、肿瘤、高血压、阿尔茨海默病、中风、心血管疾病和糖尿病。然而，关于这种化合物与男性生育能力之间的关系知之甚少，而且现有的少数结果往往存在争议。因此，本综述评估了RSV对人类男性生育能力的影响以及这种多酚作用于人类精子的机制。
