Siddiqui Shahida Anusha, Azmy Harahap Iskandar, Suthar Priyanka, Wu Yuan Seng, Ghosh Nibedita, Castro-Muñoz Roberto
Department of Biotechnology and Sustainability, Technical University of Munich, Essigberg 3, 94315 Straubing, Germany.
German Institute of Food Technologies (DIL e.V.), Prof.-von-Klitzing Str. 7, 49610 Quakenbrück, Germany.
Foods. 2023 Sep 28;12(19):3610. doi: 10.3390/foods12193610.
Obesity is a complex medical condition mainly caused by eating habits, genetics, lifestyle, and medicine. The present study deals with traditional diets like the Mediterranean diet, Nordic diet, African Heritage diet, Asian diet, and DASH, as these are considered to be sustainable diets for curing obesity. However, the bioavailability of phytonutrients consumed in the diet may vary, depending on several factors such as digestion and absorption of phytonutrients, interaction with other substances, cooking processes, and individual differences. Hence, several phytochemicals, like polyphenols, alkaloids, saponins, terpenoids, etc., have been investigated to assess their efficiencies and safety in the prevention and treatment of obesity. These phytochemicals have anti-obesity effects, mediated via modulation of many pathways, such as decreased lipogenesis, lipid absorption, accelerated lipolysis, energy intake, expenditure, and preadipocyte differentiation and proliferation. Owing to these anti-obesity effects, new food formulations incorporating these phytonutrients were introduced that can be beneficial in reducing the prevalence of obesity and promoting public health.
肥胖是一种复杂的医学状况，主要由饮食习惯、遗传因素、生活方式和药物引起。本研究涉及地中海饮食、北欧饮食、非洲传统饮食、亚洲饮食和得舒饮食等传统饮食，因为这些饮食被认为是治疗肥胖的可持续饮食。然而，饮食中摄入的植物营养素的生物利用度可能会有所不同，这取决于几个因素，如植物营养素的消化和吸收、与其他物质的相互作用、烹饪过程以及个体差异。因此，人们对几种植物化学物质，如多酚、生物碱、皂苷、萜类化合物等进行了研究，以评估它们在预防和治疗肥胖方面的功效和安全性。这些植物化学物质具有抗肥胖作用，通过调节多种途径介导，如减少脂肪生成、脂质吸收、加速脂肪分解、能量摄入、消耗以及前脂肪细胞的分化和增殖。由于这些抗肥胖作用，引入了含有这些植物营养素的新食品配方，这可能有助于降低肥胖的患病率并促进公众健康。
