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HIV感染患者的抗逆转录病毒治疗知识及相关因素

Knowledge of Antiretroviral Treatment and Associated Factors in HIV-Infected Patients.

作者信息

Van Nguyen Lam, Nguyen Thao N P, Thach Anh N, Lam Anh N, Lam Duc Q, Duong Chu X, Pham Suol T, Nguyen Thao H, Perwitasari Dyah A, Taxis Katja, Nguyen Phuong M, Nguyen Thang

机构信息

Department of Surgery, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, Vietnam.

Department of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City 900000, Vietnam.

出版信息

Healthcare (Basel). 2021 Apr 20;9(4):483. doi: 10.3390/healthcare9040483.

DOI:10.3390/healthcare9040483
PMID:33923916
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8073643/
Abstract

This study aimed to assess the knowledge of antiretroviral (ARV) treatment and the associated factors in HIV-infected patients in Vietnam. We conducted a cross-sectional descriptive study of 350 human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients being treated with ARV at outpatient clinics at Soc Trang, Vietnam, from June 2019 to December 2019. Using an interview questionnaire, patients who answered at least eight out of nine questions correctly, including some required questions, were considered to have a general knowledge of ARV treatment. Using multivariate logistic regression to identify factors associated with knowledge of ARV treatment, we found that 62% of HIV-infected patients had a general knowledge of ARV treatment, with a mean score of 8.2 (SD 1.4) out of 9 correct. A higher education level ( < 0.001); working away from home ( = 0.013); getting HIV transmitted by injecting drugs or from mother-to-child contact ( = 0.023); the presence of tension, anxiety, or stress ( = 0.005); self-reminding to take medication ( = 0.024); and a high self-evaluated adherence ( < 0.001) were found to be significantly associated with an adequate knowledge of ARV treatment. In conclusion, education programs for patients, as well as the quality of medical services and support, should be strengthened.

摘要

本研究旨在评估越南艾滋病毒感染患者对抗逆转录病毒(ARV)治疗的了解情况及相关因素。我们于2019年6月至2019年12月在越南朔庄的门诊诊所对350名正在接受抗逆转录病毒治疗的人类免疫缺陷病毒(HIV)/获得性免疫缺陷综合征(AIDS)患者进行了一项横断面描述性研究。使用访谈问卷,回答九个问题(包括一些必答题)中至少八个正确的患者被认为对抗逆转录病毒治疗有基本了解。通过多因素逻辑回归分析确定与抗逆转录病毒治疗知识相关的因素,我们发现62%的艾滋病毒感染患者对抗逆转录病毒治疗有基本了解,平均得分为8.2分(标准差1.4)(满分9分)。较高的教育水平(<0.001);离家工作(=0.013);通过注射毒品或母婴接触感染艾滋病毒(=0.023);存在紧张、焦虑或压力(=0.005);自我提醒服药(=0.024);以及较高的自我评估依从性(<0.001)被发现与对抗逆转录病毒治疗的充分了解显著相关。总之,应加强针对患者的教育项目以及医疗服务和支持的质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7680/8073643/28307175c37f/healthcare-09-00483-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7680/8073643/28307175c37f/healthcare-09-00483-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7680/8073643/28307175c37f/healthcare-09-00483-g001.jpg

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