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评估眼压及其他生物力学参数以鉴别亚临床圆锥角膜与健康角膜。

Evaluation of Intraocular Pressure and Other Biomechanical Parameters to Distinguish between Subclinical Keratoconus and Healthy Corneas.

作者信息

Peris-Martínez Cristina, Díez-Ajenjo María Amparo, García-Domene María Carmen, Pinazo-Durán María Dolores, Luque-Cobija María José, Del Buey-Sayas María Ángeles, Ortí-Navarro Susana

机构信息

FISABIO Oftalmología Médica (FOM), Anterior Segment and Cornea and External Eye Diseases Unit, Bifurcación Pío Baroja-General Avilés, 12, E-46015 Valencia, Spain.

Surgery Department, Ophthalmology, School of Medicine, University of Valencia, Av. Blasco Ibáñez, 15, E-46010 Valencia, Spain.

出版信息

J Clin Med. 2021 Apr 28;10(9):1905. doi: 10.3390/jcm10091905.

DOI:10.3390/jcm10091905
PMID:33924937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8125335/
Abstract

(1) Purpose: To assess the main corneal response differences between normal and subclinical keratoconus (SCKC) with a Corvis ST device. (2) Material and Methods: We selected 183 eyes of normal patients, of a mean age of 33 ± 9 years and 16 eyes of patients with SCKC of a similar mean age. We measured best corrected visual acuity (BCVA) and corneal topography with a Pentacam HD device to select the SCKC group. Biomechanical measurements were performed using the Corvis ST device. We carried out a non-parametric analysis of the data with SPSS software (Wilcoxon signed rank-test). (3) Results: We found statistically significant differences between the control and SCKC groups in some corneal biomechanical parameters: first and second applanation time ( = 0.05 and = 0.02), maximum deformation amplitude ( = 0.016), highest concavity radius ( = 0.007), and second applanation length and corneal velocity (( = 0.039 and = 0.016). (4) Conclusions: Our results show that the use of normalised biomechanical parameters provided by noncontact tonometry, combined with a discriminant function theory, is a useful tool for detecting subclinical keratoconus.

摘要

(1) 目的：使用Corvis ST设备评估正常人与亚临床圆锥角膜（SCKC）患者角膜主要反应的差异。(2) 材料与方法：我们选取了183例平均年龄为33±9岁的正常患者的眼睛以及16例平均年龄相近的SCKC患者的眼睛。我们使用Pentacam HD设备测量最佳矫正视力（BCVA）和角膜地形图以选择SCKC组。使用Corvis ST设备进行生物力学测量。我们使用SPSS软件对数据进行非参数分析（Wilcoxon符号秩检验）。(3) 结果：我们发现对照组与SCKC组在一些角膜生物力学参数上存在统计学显著差异：首次和第二次压平时间（P = 0.05和P = 0.02）、最大变形幅度（P = 0.016）、最大凹陷半径（P = 0.007）以及第二次压平长度和角膜速度（P = 0.039和P = 0.016）。(4) 结论：我们的结果表明，使用非接触眼压测量法提供的标准化生物力学参数，并结合判别函数理论，是检测亚临床圆锥角膜的有用工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/8d76439a0ecc/jcm-10-01905-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/964e1b38b334/jcm-10-01905-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/545ed16f979f/jcm-10-01905-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/3b13658fa44d/jcm-10-01905-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/02918c4aa345/jcm-10-01905-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/8d76439a0ecc/jcm-10-01905-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/964e1b38b334/jcm-10-01905-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/545ed16f979f/jcm-10-01905-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/3b13658fa44d/jcm-10-01905-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/02918c4aa345/jcm-10-01905-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fada/8125335/8d76439a0ecc/jcm-10-01905-g005.jpg

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