癌症的物理特征可作为改善免疫疗法的新靶点。
Cancer Physical Hallmarks as New Targets for Improved Immunotherapy.
机构信息
Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China; Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University, Xi'an 710049, P.R. China.
Department of Medical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710061, P.R. China; Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University, Xi'an 710049, P.R. China.
出版信息
Trends Cell Biol. 2021 Jul;31(7):520-524. doi: 10.1016/j.tcb.2021.03.011. Epub 2021 Apr 27.
A low response rate is the major challenge for existing cancer immunotherapies. Physical cues in the tumor microenvironment (TME) have been recognized as new hallmarks of cancer, which may synergistically contribute to low immunotherapy response. Recent evidence indicates that the physical hallmarks of cancer hold great potential as new targets for improved immunotherapy.
低应答率是现有癌症免疫疗法面临的主要挑战。肿瘤微环境（TME）中的物理线索已被认为是癌症的新标志，它们可能协同作用导致免疫治疗反应低下。最近的证据表明，癌症的物理特征具有作为改善免疫治疗的新靶点的巨大潜力。
Zotero 插件