Department of Neurology, Päijät-Häme Joint Municipal Authority, Hämeenlinna, Finland.
Clinical Genetics, Turku University Hospital, Turku, Finland.
J Appl Res Intellect Disabil. 2021 Nov;34(6):1463-1467. doi: 10.1111/jar.12888. Epub 2021 May 1.
In intellectual disability, the cognitive delay is observed during developmental age, whereas in dementia, cognitive decline occurs during post-developmental period. So far, the risk of dementia in people with intellectual disability, excluding those with Down syndrome, is poorly known.
We screened dementia signs in a study group of 230 adults (34-80 years of age) with the help of the British Present Psychiatric State-Learning Disabilities assessment.
Of the study members, 42% showed two or more signs. The overall frequency of symptoms did not differ between age groups. The number of individuals with a genetic syndrome or disease manifesting with a shortened lifespan was greater in the younger age groups when compared to the older age groups.
People with an intellectual disability represent numerous rare syndromes with comorbidities. It seems that dementia signs may affect any age groups of adults with intellectual disability.
在智力障碍中，认知延迟发生在发育时期，而在痴呆中，认知能力下降发生在发育后期。到目前为止，除唐氏综合征患者外，人们对智力障碍患者（不包括唐氏综合征患者）的痴呆风险知之甚少。
我们使用英国当前精神病学状态-学习障碍评估工具，帮助研究小组筛查了 230 名成年人（34-80 岁）的痴呆迹象。
研究对象中，42%的人出现了两个或更多的迹象。各年龄组的症状总发生率没有差异。与年龄较大的年龄组相比，年龄较小的年龄组中具有缩短寿命的遗传综合征或疾病表现的个体数量更多。
智力障碍患者代表了许多具有合并症的罕见综合征。似乎痴呆症状可能会影响任何年龄段的智力障碍成年人。
