Specialized Service in Mental Health and Intellectual Disability, Institute of Health Assistance, Parc Hospitalari Martí i Julià, Catalonia, 17190 Girona, Spain.
Research and Psychology in Education Department, Complutense University of Madrid, 28040 Madrid, Spain.
Int J Environ Res Public Health. 2022 Aug 30;19(17):10780. doi: 10.3390/ijerph191710780.
In this study, we examined normative data and diagnostic accuracy of a pictorial screening test to detect memory impairment for mild cognitive impairment (MCI) and Alzheimer's disease (AD) in Spanish-speaking adults with intellectual disability (ID). A total of 94 volunteers with ID (60 controls, 17 MCI, and 17 AD), were evaluated by neuropsychological tests including the PMIS-ID in a cross-sectional validation study. Discriminative validity between the MCI, AD, and control group was analyzed by the area under the ROC curve. A cut-off score of 4.5 on the immediate recall trial had a sensitivity of 69% and a specificity of 80% to detect memory impairment (AUC = 0.685; 95% CI = 0.506-0.863) in the AD group. The PMIS-ID is a useful screening test to rule out a diagnosis of memory decline in people with moderate level of ID and AD, and it shows good psychometric properties.
在这项研究中，我们研究了一种图片筛查测试的规范数据和诊断准确性，以检测西班牙语智力障碍（ID）成年人中轻度认知障碍（MCI）和阿尔茨海默病（AD）的记忆障碍。共有 94 名 ID 志愿者（60 名对照、17 名 MCI 和 17 名 AD）参加了横断面验证研究，通过神经心理学测试（包括 PMIS-ID）进行评估。通过 ROC 曲线下的面积分析 MCI、AD 和对照组之间的判别有效性。在 AD 组中，即时回忆试验中 4.5 的截断分数对检测记忆障碍的敏感性为 69%，特异性为 80%（AUC = 0.685；95%CI = 0.506-0.863）。PMIS-ID 是一种有用的筛查测试，可以排除中度 ID 和 AD 人群的记忆下降诊断，并且具有良好的心理计量特性。
