-mutated malignant melanoma with chondrosarcomatous differentiation in inguinal nodal metastasis.
作者信息
Abbati Francesca, Altimari Annalisa, Corti Barbara, Dika Emi, Sperandi Francesca, Melotti Barbara
机构信息
Department of Medical Oncology IRCCS Azienda Ospedaliero-Universitaria di Bologna Bologna Italy.
Laboratory of Oncologic Molecular Pathology IRCCS Azienda Ospedaliero-Universitaria di Bologna Bologna Italy.
出版信息
Clin Case Rep. 2021 Mar 7;9(4):2200-2204. doi: 10.1002/ccr3.3982. eCollection 2021 Apr.
We report the case of a young woman who developed metastatic melanoma in the inguinal nodal region, which acquired chondrosarcomatous differentiation and preserved the BRAF mutation found in the primary tumor. The patient was treated with a BRAF/MEK inhibitor combination therapy (dabrafenib/trametinib), which was demonstrated to be effective and well-tolerated.
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