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仅接受类固醇治疗且预后良好的患者发生原发性渗出性淋巴瘤。

Primary effusion lymphoma in a patient with a good outcome on steroid alone treatment.

作者信息

Koren Ofir, Aviv Ariel, Kelbert Moran Avraham, Rozner Ehud, Lihtman Liza, Halfin Elya, Turgeman Yoav

机构信息

Heart Institute Emek Medical Center Afula Israel.

Bruce Rappaport Faculty of Medicine Technion Israel Institute of Technology Haifa Israel.

出版信息

Clin Case Rep. 2021 Mar 4;9(4):2305-2309. doi: 10.1002/ccr3.4020. eCollection 2021 Apr.

DOI:10.1002/ccr3.4020
PMID:33936684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8077339/
Abstract

Same clinical entity can have different biology and can behave differently. This must be kept in mind while making therapeutic decisions. Primary effusion lymphoma is a rare and devastating disease with high fatality. Chemotherapy provides limited benefit. We describe a unique case of a good outcome with steroid alone treatment.

摘要

相同的临床实体可能具有不同的生物学特性,表现也可能不同。在做出治疗决策时必须牢记这一点。原发性渗出性淋巴瘤是一种罕见且具有毁灭性的疾病,死亡率很高。化疗的益处有限。我们描述了一例仅用类固醇治疗就取得良好疗效的独特病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd2/8077339/431265e013d8/CCR3-9-2305-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd2/8077339/4e2e64779604/CCR3-9-2305-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd2/8077339/c5a9b633f8eb/CCR3-9-2305-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd2/8077339/a6cc7e4156d9/CCR3-9-2305-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd2/8077339/431265e013d8/CCR3-9-2305-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd2/8077339/4e2e64779604/CCR3-9-2305-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd2/8077339/c5a9b633f8eb/CCR3-9-2305-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd2/8077339/a6cc7e4156d9/CCR3-9-2305-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fd2/8077339/431265e013d8/CCR3-9-2305-g005.jpg

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本文引用的文献

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Blood. 2019 Apr 18;133(16):1753-1761. doi: 10.1182/blood-2019-01-893339. Epub 2019 Feb 19.
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Multiple remissions of extracavitary primary effusion lymphoma treated with a single cycle of liposomal doxorubicin in a patient infected with HIV.一名感染HIV的患者接受单周期脂质体阿霉素治疗后,腔外原发性渗出性淋巴瘤多次缓解。
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原发性渗出性淋巴瘤:当前观点
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Primary effusion lymphoma: current concepts and management.原发性渗出性淋巴瘤:当前概念与管理
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Classification of AIDS-related lymphoma cases between 1987 and 2012 in Japan based on the WHO classification of lymphomas, fourth edition.根据世界卫生组织(WHO)第四版淋巴瘤分类,对 1987 年至 2012 年期间日本的艾滋病相关淋巴瘤病例进行分类。
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PEL and HHV8-unrelated effusion lymphomas: classification and diagnosis.原发性渗出性淋巴瘤及与人类疱疹病毒8型无关的渗出性淋巴瘤:分类与诊断
Cancer. 2008 Aug 25;114(4):225-7. doi: 10.1002/cncr.23597.
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Distinct subsets of primary effusion lymphoma can be identified based on their cellular gene expression profile and viral association.原发性渗出性淋巴瘤的不同亚群可根据其细胞基因表达谱和病毒关联来识别。
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