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新冠病毒肺炎患者血型亚群与PCR检测阳性及肺部受累的相关性

Association of Blood Subgroups With PCR Test Positivity and Lung Involvement in Patients With COVID-19.

作者信息

Coluk Yonca, Hizli Omer, Gunaydın Selda, Yildirim Guven, Baysal Elif, Ozgen Hergul Guliz

机构信息

Department of Otolaryngology, Giresun University, Faculty of Medicine, Giresun, TUR.

Department of Otolaryngology, Balikesir University, Faculty of Medicine, Balikesir, TUR.

出版信息

Cureus. 2021 Mar 29;13(3):e14172. doi: 10.7759/cureus.14172.

Abstract

Objective The goal of this study was to investigate whether blood group type caused susceptibility to COVID-19 infection. Methods Two hundred and eleven consecutive patients admitted with various symptoms associated with COVID-19 were included. We compared the AB0 and Rh subgroup distributions between patients with a positive polymerase chain reaction (PCR) test result and the patients without. We compared the AB0 and Rh subgroup distributions between patients with lung involvement and patients without. Additionally, comparisons were performed between the patients both with positive PCR result and lung involvement, and the patients with a negative PCR result. Results No significant difference of ABO and Rh subgroup distributions was evident between patients with and without a positive PCR test result (p=0.632 and p=0.962). No significant difference of ABO and Rh subgroup distributions was evident between the patients with and without lung involvement (p=0.097 and p=0.797). No significant difference of ABO and Rh subgroup distributions was evident among patients both with PCR positivity and lung involvement, patients with only PCR positivity, and the patients with negative PCR test results (p=0.3 and p=0.993). Conclusion All blood group types seem to have an equal risk of COVID-19 infection. Everyone should follow the precautions to avoid the COVID-19 infection.

摘要

目的 本研究的目的是调查血型是否会导致对新型冠状病毒肺炎(COVID-19)感染的易感性。方法 纳入211例因与COVID-19相关的各种症状而入院的连续患者。我们比较了聚合酶链反应(PCR)检测结果呈阳性的患者与检测结果为阴性的患者之间的ABO和Rh亚组分布。我们比较了有肺部受累的患者与无肺部受累的患者之间的ABO和Rh亚组分布。此外,还对PCR结果呈阳性且有肺部受累的患者与PCR结果为阴性的患者进行了比较。结果 PCR检测结果呈阳性的患者与检测结果为阴性的患者之间,ABO和Rh亚组分布无明显差异(p=0.632和p=0.962)。有肺部受累的患者与无肺部受累的患者之间,ABO和Rh亚组分布无明显差异(p=0.097和p=0.797)。PCR呈阳性且有肺部受累的患者、仅PCR呈阳性的患者与PCR检测结果为阴性的患者之间,ABO和Rh亚组分布无明显差异(p=0.3和p=0.993)。结论 所有血型似乎感染COVID-19的风险均等。每个人都应遵循预防措施以避免感染COVID-19。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b044/8080950/63bffb1e2935/cureus-0013-00000014172-i01.jpg

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