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三级医疗保健中心新冠肺炎患者的耳鼻喉科表现研究

A Study on Otorhinolaryngological Presentations in Covid 19 Patients in a Tertiary Health Care Center.

作者信息

Smitha S G, Pillai Nikitha, Nayak Bindya, Raveendran Jedhin

机构信息

Department of ENT, Kims Hospital, Bangalore, Karnataka India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):2935-2940. doi: 10.1007/s12070-021-02564-2. Epub 2021 Apr 27.

Abstract

Corona virus also known as 2019 novel corona virus, a single stranded positive sense RNA virus is the causative agent of COVID 19 disease. It mainly spreads via the respiratory route by means of aerosols. The objectives of our study were. To know the prevalence of ENT presentations in COVID 19 patients and to know the relationship between the symptoms and category of the disease as well as to know the relation between the blood group and recovery from the disease. The first 500 patients who were tested positive for COVID 19 and getting treated in our hospital were included in the study after taking written informed consent from the patients who were willing to participate in the study. A detailed history was taken from all the patients and more stress was given on the ENT symptoms with respect to its onset, duration and time taken for the relief of symptoms. The ENT symptoms were compared with the category of the disease as well as the blood group of the patients. Statistical analysis was done using Chi square test and Statistical Package for Social Sciences [SPSS] for Windows Version 22.0 Released 2013. Armonk, NY: IBM Corp., was used to perform statistical analyses. In our study 310 (62.0%) were males and 190 (38.0%) patients were females (38%), of age group ranging from 2 years to 87 years. In our study 367 (73.3%) patients were symptomatic and the rest 133 (26.6%) were asymptomatic. There were 335 (67.0%) patients in category A, 140 (28.0%) in category B and 25 (5.0%) in category C. The most common ENT presentation was headache and its prevelance was more in category C and it was of statistical significance. On comparing the blood group and the ENT symptoms occurrence of sore throat was of statistical significance and its prevelance was more among the O blood group patients. In terms of recovery from the disease the patients with blood group O had good recovery rate. Covid 19 pandemic is still an on going problem and newer strains of the virus are arising as well hence. In our study we found out that isolated ENT symptoms such as aguesia and anosmia were the only presentation of the disease. Thus they can be considered as early marker of the disease and it will be helpful in early detection and isolation of the patient as well as prevention of further spread of the disease.

摘要

冠状病毒也被称为2019新型冠状病毒,是一种单链正链RNA病毒,是新冠肺炎疾病的病原体。它主要通过气溶胶经呼吸道传播。我们研究的目的是:了解新冠肺炎患者耳鼻喉科症状的患病率,了解症状与疾病类别之间的关系,以及了解血型与疾病康复之间的关系。在获得愿意参与研究的患者的书面知情同意后,我们纳入了在我院接受治疗的首批500例新冠肺炎检测呈阳性的患者。我们收集了所有患者的详细病史,并特别关注耳鼻喉科症状的发作、持续时间以及症状缓解所需的时间。将耳鼻喉科症状与疾病类别以及患者的血型进行了比较。使用卡方检验和社会科学统计软件包[SPSS]Windows版本22.0(2013年发布,纽约州阿蒙克:IBM公司)进行统计分析。在我们的研究中,310名(62.0%)为男性,190名(38.0%)为女性,年龄范围从2岁到87岁。在我们的研究中,367名(73.3%)患者有症状,其余133名(26.6%)无症状。A类患者有335名(67.0%),B类患者有140名(28.0%),C类患者有25名(5.0%)。最常见的耳鼻喉科症状是头痛,其患病率在C类中更高,具有统计学意义。在比较血型与耳鼻喉科症状时,喉咙痛的发生率具有统计学意义,且在O型血患者中患病率更高。就疾病康复而言,O型血患者的康复率良好。新冠疫情仍然是一个持续存在的问题,并且新的病毒株也在不断出现。在我们的研究中,我们发现诸如味觉丧失和嗅觉丧失等孤立的耳鼻喉科症状是该疾病的唯一表现。因此,它们可被视为该疾病的早期标志物,这将有助于早期发现和隔离患者以及预防疾病的进一步传播。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/84c7/9702367/533cd609e8c8/12070_2021_2564_Fig1_HTML.jpg

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