Gupta Semridhi, Kumbhat Payal, Seervi Manohar
Department of Otorhinolaryngology and Head and Neck Surgery, Dr. S. N. Medical College and M.D.M. Hospital, Jodhpur, Rajasthan 342003 India.
Near Lachoo College, A-44, Shastri Nagar, Jodhpur, Rajasthan 342003 India.
Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):2930-2934. doi: 10.1007/s12070-021-02563-3. Epub 2021 Apr 27.
Coronavirus causes damage to chemosensory receptors resulting in olfactory and gustatory dysfunction. This study reports our observations on anosmia and ageusia in symptomatic COVID-19 positive patients admitted in the COVID centre of Western Rajasthan. A total of 98 symptomatic, RT-PCR positive COVID-19 patients admitted in the M.G. Hospital during November 2020 were evaluated with detailed history regarding symptoms along with duration and resolution including response to antiviral therapy. Olfactory and Gustatory dysfunction was seen in 53.1% patients. Both anosmia and ageusia coexisted in 61.5% patients followed by isolated anosmia (25%), while isolated ageusia was rare. History of preceding fever was present in 69.2% cases. 100% of the patients with ageusia had loss of salty and sour taste, while 90.1% did not feel sweet taste. Bitter taste sensation was altered only in 63.6%. Symptoms reversed within 7 days in 94.2% cases and after 15 days in 5.8% cases irrespective of antiviral therapy. Chemosensory dysfunction has no racial predominance. It is a self-limiting manifestation and a useful screening symptom. Co-existence of anosmia and ageusia is more common than isolated dysfunction. In ageusia, salty and sour is the most commonly lost taste sensation followed by sweet.
冠状病毒会对化学感应受体造成损害，导致嗅觉和味觉功能障碍。本研究报告了我们对拉贾斯坦邦西部新冠中心收治的有症状的新冠病毒检测呈阳性患者嗅觉丧失和味觉丧失情况的观察结果。对2020年11月期间在M.G.医院收治的98例有症状、RT-PCR检测呈阳性的新冠患者进行了评估，详细询问了症状、持续时间和恢复情况，包括对抗病毒治疗的反应。53.1%的患者出现了嗅觉和味觉功能障碍。61.5%的患者同时存在嗅觉丧失和味觉丧失，其次是单纯嗅觉丧失（25%），而单纯味觉丧失则较为罕见。69.2%的病例有先前发热史。100%的味觉丧失患者失去了咸和酸味觉，而90.1%的患者感觉不到甜味。只有63.6%的患者苦味觉发生了改变。无论是否接受抗病毒治疗，94.2%的病例症状在7天内缓解，5.8%的病例在15天后缓解。化学感应功能障碍没有种族优势。它是一种自限性表现，也是一种有用的筛查症状。嗅觉丧失和味觉丧失同时存在比单纯功能障碍更为常见。在味觉丧失中，咸和酸味觉是最常丧失的味觉，其次是甜味。
