Makivic Nina, Stöllberger Claudia, Schauer Dominic, Bernhofer Laura, Pawelka Erich, Erfurth Andreas, Weidinger Franz
Department of Cardiology, Klinik Landstrasse, Vienna, Austria.
Department of Radiology, Klinik Landstrasse, Vienna, Austria.
SN Compr Clin Med. 2021;3(6):1434-1439. doi: 10.1007/s42399-021-00925-0. Epub 2021 Apr 27.
The increased risk for thromboembolism in hospitalized COVID-19 patients has been communicated extensively. The fact that home quarantined patients can develop pulmonary embolism, however, has so far not been reported. Furthermore, attention should be brought to psychotic developments in COVID-19 patients. We report a 46-year-old previously healthy patient with a mild course of COVID-19, who developed a massive pulmonary embolism with right heart strain while being home quarantined. He was hospitalized and anticoagulant therapy was started. Nine days after admission, the patient appeared increasingly psychotic and suffered from hallucinations as well as paranoid thoughts. After treatment with risperidone and valproate, the patient's condition improved. At a follow-up 1 month after discharge, he was completely recovered regarding the respiratory, cardiac, and psychic situation. SARS-CoV-2 infection can not only increase the prevalence of thromboembolism in hospitalized patients but also in outpatients. COVID-19 also increases the risk of developing psychiatric reactions.
住院的新冠病毒疾病（COVID-19）患者发生血栓栓塞的风险增加，这一点已被广泛报道。然而，居家隔离患者会发生肺栓塞这一情况，目前尚未见报道。此外，新冠病毒疾病患者的精神状态变化也应引起关注。我们报告一例46岁既往健康的患者，其新冠病毒疾病病情较轻，在居家隔离期间发生了大面积肺栓塞并伴有右心劳损。他被收治入院并开始接受抗凝治疗。入院九天后，患者精神状态逐渐异常，出现幻觉及偏执想法。经利培酮和丙戊酸盐治疗后，患者病情好转。出院1个月后的随访显示，其呼吸、心脏及精神状态已完全恢复。严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染不仅会增加住院患者血栓栓塞的发生率，也会增加门诊患者的发生率。新冠病毒疾病还会增加发生精神反应的风险。
