Department of Otolaryngology, Sawada Eye and Ear Clinic, Fukuicho, Kochi City, Kochi, Japan.
Department of Otolaryngology, Matsubara ENT Clinic, Gifu, Japan.
Laryngoscope. 2021 Oct;131(10):E2705-E2711. doi: 10.1002/lary.29564. Epub 2021 May 3.
OBJECTIVES/HYPOTHESIS: Acute rhinosinusitis is a frequent common cold-related complication in children. Despite the need for appropriate treatment, its underlying microbiology remains unclear. This study aimed to investigate the microbiology of acute rhinosinusitis in children.
Prospective non controlled study.
Thirty-one pediatric acute maxillary sinusitis patients with severe symptoms were assessed. The subjects were 17 males and 14 females aged 5 to 14 years (mean age, 9.1 years). Maxillary sinus aspirates were collected and cultured, with subsequent viral and bacterial polymerase chain reaction (PCR) analysis. Bacteria were analyzed using culturing and PCR, and viruses were analyzed using PCR. The PCR kits used identify 18 types of respiratory viruses and 13 types of bacteria.
At least one pathogen was detected in 30 of 31 aspirates (97%) using PCR, and none of the aspirates contained respiratory viruses alone. Ten aspirates (32%) contained both viruses and bacteria. The most common viruses detected were rhinovirus (13%) and influenza virus (10%). The most common bacteria were Haemophilus influenzae (45%), Streptococcus pneumoniae (32%), Moraxella catarrhalis (16%), and Chlamydophila pneumoniae (13%). Bacteria were found in 21 of 31 cases (68%) via bacterial culturing. Culturing revealed that H influenzae was the most common pathogen (42%).
In pediatric acute maxillary sinusitis, respiratory bacteria were detected in 65% of the sinus aspirates and both bacteria and viruses in 32%. The most common viruses were rhinovirus and influenza virus, and the most common bacteria were H influenzae and S pneumoniae. Viral and bacterial PCR is useful for accurately investigating the microbiology in pediatric sinusitis.
3 Laryngoscope, 131:E2705-E2711, 2021.
目的/假设：急性鼻-鼻窦炎是儿童常见的普通感冒相关并发症。尽管需要进行适当的治疗，但其潜在的微生物学仍不清楚。本研究旨在调查儿童急性鼻-鼻窦炎的微生物学。
前瞻性非对照研究。
评估了 31 例患有严重症状的儿科急性上颌窦炎患者。这些患者为 17 名男性和 14 名女性，年龄 5 至 14 岁（平均年龄 9.1 岁）。采集上颌窦吸出物进行培养，并进行病毒和细菌聚合酶链反应（PCR）分析。细菌通过培养和 PCR 进行分析，病毒通过 PCR 进行分析。使用的 PCR 试剂盒可鉴定 18 种呼吸道病毒和 13 种细菌。
31 个吸出物中，通过 PCR 检测到至少一种病原体的有 30 个（97%），且没有一个吸出物仅含有呼吸道病毒。10 个吸出物（32%）同时含有病毒和细菌。最常见的病毒是鼻病毒（13%）和流感病毒（10%）。最常见的细菌是流感嗜血杆菌（45%）、肺炎链球菌（32%）、卡他莫拉菌（16%）和肺炎衣原体（13%）。通过细菌培养，在 31 例病例中发现了 21 例（68%）细菌。培养结果显示，流感嗜血杆菌是最常见的病原体（42%）。
在儿科急性上颌窦炎中，鼻窦吸出物中检测到呼吸道细菌的占 65%，同时存在细菌和病毒的占 32%。最常见的病毒是鼻病毒和流感病毒，最常见的细菌是流感嗜血杆菌和肺炎链球菌。病毒和细菌 PCR 有助于准确调查儿科鼻窦炎的微生物学。
3 级喉镜，131：E2705-E2711，2021 年。
