1991年至2000年间日本肺炎衣原体的血清流行病学研究。
Seroepidemiology of Chlamydia pneumoniae in Japan between 1991 and 2000.
作者信息
Miyashita N, Fukano H, Yoshida K, Niki Y, Matsushima T
机构信息
Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Kurashika City, Okayama, Japan.
出版信息
J Clin Pathol. 2002 Feb;55(2):115-7. doi: 10.1136/jcp.55.2.115.
AIM
To clarify the endemic and epidemic status of Chlamydia pneumoniae in Japan, the incidence of anti-C pneumoniae antibody was evaluated over a period of 10 years.
METHOD
Serum samples were collected from 4756 healthy individuals aged 6 months to 88 years (2488 male and 2268 female individuals) between 1991 and 2000. The antibody titre was determined by a microimmunofluorescence test.
RESULTS
After stratification by age and sex in each year, distinct peaks with prevalences of 73.3% and 73.0% were noted in 1993 and 1999, respectively. The lowest prevalence rate was seen in 1996 (59.0%). The epidemic cycle has been estimated to be almost six years in this geographical area.
CONCLUSIONS
Chlamydia pneumoniae infection is highly endemic in Japan, as it is in Western countries, and there is a year to year variability. Long term studies in Japan are needed to clarify the epidemic occurrence of C pneumoniae infection.
目的
为阐明日本肺炎衣原体的地方流行和流行状况，对10年间抗肺炎衣原体抗体的发生率进行了评估。
方法
在1991年至2000年间，从4756名年龄在6个月至88岁之间的健康个体（男性2488名，女性2268名）中采集血清样本。通过微量免疫荧光试验测定抗体滴度。
结果
每年按年龄和性别分层后，分别在1993年和1999年观察到明显的峰值，患病率分别为73.3%和73.0%。最低患病率出现在1996年（59.0%）。据估计，该地理区域的流行周期约为六年。
结论
与西方国家一样，肺炎衣原体感染在日本高度流行，且存在逐年变化。需要在日本进行长期研究以阐明肺炎衣原体感染的流行情况。
Zotero 插件