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静脉管道中的肌肉:我们的经验。

Muscle in vein conduits: our experience.

机构信息

Clinica Ortopedica dell'Università degli Studi di Brescia.

Clinica ortopedica dell' Università degli studi di Brescia.

出版信息

Acta Biomed. 2021 Apr 30;92(S1):e2021163. doi: 10.23750/abm.v92iS1.9202.

DOI:10.23750/abm.v92iS1.9202
PMID:33944845
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8142788/
Abstract

Muscle in vein (MIV ) conduits have gradually been employed in the last 20 years as a valuable technique in bridging peripheral nerve gaps after nerve lesions who cannot undergo a direct tension-free coaptation. The advantages of this procedure comparing to the actual benchmark (autograft) is the sparing of the donor site, and the huge availability of both components (i.e. muscle and veins). Here we present a case serie of four MIV performed at our hospital from 2018 to 2019. The results we obtained in our experi-ence confirmed its effectiveness both in nerve regeneration (as sensibility recovery) and in neuropathic pain eradication. Our positive outcomes encourage its use in selected cases of residual nerve gaps up to 30 mm.

摘要

静脉内肌(MIV)移植物在过去 20 年中逐渐被用作治疗神经损伤后无法进行直接无张力吻合的周围神经间隙的一种有价值的技术。与实际的基准(自体移植物)相比,该手术的优点是可以避免供体部位损伤,并且两种成分(即肌肉和静脉)都非常丰富。在此,我们介绍了 2018 年至 2019 年在我院进行的 4 例 MIV 病例系列。我们的经验结果证实了其在神经再生(如感觉恢复)和消除神经病理性疼痛方面的有效性。我们的积极结果鼓励在最大达 30mm 的残余神经间隙的选定病例中使用该方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/524a/8142788/cdbd881b2a03/ACTA-92-163-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/524a/8142788/d5981d27401f/ACTA-92-163-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/524a/8142788/fc2e1682ac52/ACTA-92-163-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/524a/8142788/5c30568830c5/ACTA-92-163-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/524a/8142788/cdbd881b2a03/ACTA-92-163-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/524a/8142788/d5981d27401f/ACTA-92-163-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/524a/8142788/fc2e1682ac52/ACTA-92-163-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/524a/8142788/5c30568830c5/ACTA-92-163-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/524a/8142788/cdbd881b2a03/ACTA-92-163-g004.jpg

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本文引用的文献

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Peripheral Nerve Conduit: Materials and Structures.周围神经导管:材料与结构。
ACS Chem Neurosci. 2019 Aug 21;10(8):3349-3365. doi: 10.1021/acschemneuro.9b00203. Epub 2019 Jul 5.
2
Efficacy of Human Cell-Seeded Muscle-Stuffed Vein Conduit in Rat Sciatic Nerve Repair.人源细胞种植肌管静脉移植物修复大鼠坐骨神经缺损的疗效。
Tissue Eng Part A. 2019 Oct;25(19-20):1438-1455. doi: 10.1089/ten.TEA.2018.0279. Epub 2019 Aug 20.
3
Bridging the gap in peripheral nerve repair with 3D printed and bioprinted conduits.用 3D 打印和生物打印导管弥合周围神经修复的差距。
Biomaterials. 2018 Dec;186:44-63. doi: 10.1016/j.biomaterials.2018.09.010. Epub 2018 Sep 12.
4
Chitosan Tubes Enriched with Fresh Skeletal Muscle Fibers for Primary Nerve Repair.富含新鲜骨骼肌纤维的壳聚糖管用于初级神经修复。
Biomed Res Int. 2018 Jun 13;2018:9175248. doi: 10.1155/2018/9175248. eCollection 2018.
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Nerve conduits for treating peripheral nerve injuries: A systematic literature review.用于治疗周围神经损伤的神经导管:一项系统文献综述。
Hand Surg Rehabil. 2017 Apr;36(2):71-85. doi: 10.1016/j.hansur.2016.10.212. Epub 2017 Jan 25.
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Autograft Substitutes: Conduits and Processed Nerve Allografts.自体移植替代物:导管与处理过的同种异体神经移植物。
Hand Clin. 2016 May;32(2):127-40. doi: 10.1016/j.hcl.2015.12.012.
7
Influence of immobilization and sensory re-education on the sensory recovery after reconstruction of digital nerves with direct suture or muscle-in-vein conduits.固定和感觉再训练对采用直接缝合或肌-静脉导管修复指神经后感觉恢复的影响。
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