Kuhar Urška, Žele Vengušt Diana, Jamnikar-Ciglenečki Urška, Vengušt Gorazd
Institute of Microbiology and Parasitology, Veterinary Faculty, University of Ljubljana, Gerbičeva 60, 1000 Ljubljana, Slovenia.
Institute of Pathology, Wild Animals, Fish and Bees, Veterinary Faculty, University of Ljubljana, Gerbičeva 60, 1000 Ljubljana, Slovenia.
Pathogens. 2021 Apr 30;10(5):539. doi: 10.3390/pathogens10050539.
Papillomaviruses (PVs) are an extremely large group of viruses that cause skin and mucosal infections in humans and various domestic and wild animals. Nevertheless, there is limited knowledge about PVs in wildlife hosts, including mustelid species. This study describes a case in stone marten () with a clinical manifestation of skin tumor, which is rather atypical for infections with PVs. The result of the papillomavirus PCR performed on the skin tumor sample was positive, and the complete PV genome was determined in the studied sample using next-generation sequencing technology. The analysis of the PV genome revealed infection of the stone marten with a putative new PV type belonging to the genus. The proposed new stone marten PV type was named MfoiPV1.
乳头瘤病毒（PVs）是一类极其庞大的病毒，可导致人类以及各种家养和野生动物的皮肤和黏膜感染。然而，对于包括鼬科动物在内的野生动物宿主中的PVs，我们了解有限。本研究描述了一例石貂（）出现皮肤肿瘤临床表现的病例，这在PVs感染中相当不典型。对皮肤肿瘤样本进行的乳头瘤病毒PCR检测结果呈阳性，并使用新一代测序技术在研究样本中确定了完整的PV基因组。PV基因组分析显示，石貂感染了一种属于属的假定新PV型。提议的新石貂PV型被命名为MfoiPV1。
