Department for Nutrition, Institute for Sports and Sports Science, University of Freiburg, Schwarzwaldstr 175, 79117 Freiburg, Germany.
CRI, Collagen Research Institute, Schauenburgerstr 116, 24118 Kiel, Germany.
Int J Environ Res Public Health. 2021 Apr 30;18(9):4837. doi: 10.3390/ijerph18094837.
It has been shown that specific collagen peptides combined with resistance training (RT) improves body composition and muscle strength in elderly sarcopenic men. The main purpose of this RCT study was to investigate the efficacy of the identical specific collagen peptides combined with RT on body composition and muscle strength in middle-aged, untrained men. Furthermore, in the exploratory part of the study, these results were compared with another group that had received whey protein in addition to the RT. Ninety-seven men completed this study and participated in a 12-week RT program. They ingested 15 g of specific collagen peptides (n = 30; CP-G), placebo (n = 31; P-G), or whey protein (n = 36; WP-G) daily. Changes in fat free mass and fat mass were determined by dual-energy X-ray absorptiometry (DXA), and isometric leg strength was measured. All participants had significantly ( < 0.01) improved levels in fat free mass (ΔCP-G = 3.42 ± 2.54 kg; ΔP-G = 1.83 ± 2.09 kg; ΔWP-G = 2.27 ± 2.56 kg), fat mass (ΔCP-G = -5.28 ± 3.19 kg; ΔP-G = -3.39 ± 3.13 kg; ΔWP-G = -4.08 ± 2.80 kg) and leg strength (ΔCP-G = 163 ± 189 N; ΔP-G = 100 ± 154 N; ΔWP-G = 120 ± 233 N). The main analysis revealed a statistically significantly higher increase in fat free mass ( = 0.010) and decrease in fat mass ( = 0.023) in the CP-G compared with the P-G. The exploratory analysis showed no statistically significant differences between WP-G and CP-G or P-G, regarding changes of fat free mass and fat mass. In conclusion, specific collagen peptide supplementation combined with RT was associated with a significantly greater increase in fat free mass and a decrease in fat mass compared with placebo. RT combined with whey protein also had a positive impact on body composition, but the respective effects were more pronounced following the specific collagen peptide administration.
已经证明，特定的胶原蛋白肽与阻力训练（RT）相结合可以改善老年男性肌肉减少症患者的身体成分和肌肉力量。本 RCT 研究的主要目的是研究相同的特定胶原蛋白肽与 RT 结合对中年未经训练男性身体成分和肌肉力量的疗效。此外，在研究的探索性部分，将这些结果与另一组接受 RT 加乳清蛋白的结果进行比较。97 名男性完成了这项研究，并参加了为期 12 周的 RT 计划。他们每天摄入 15 克特定胶原蛋白肽（n = 30；CP-G）、安慰剂（n = 31；P-G）或乳清蛋白（n = 36；WP-G）。通过双能 X 射线吸收法（DXA）测定去脂体重和脂肪量的变化，并用等长腿部力量进行测量。所有参与者的去脂体重（ΔCP-G = 3.42 ± 2.54 kg；ΔP-G = 1.83 ± 2.09 kg；ΔWP-G = 2.27 ± 2.56 kg）、脂肪量（ΔCP-G = -5.28 ± 3.19 kg；ΔP-G = -3.39 ± 3.13 kg；ΔWP-G = -4.08 ± 2.80 kg）和腿部力量（ΔCP-G = 163 ± 189 N；ΔP-G = 100 ± 154 N；ΔWP-G = 120 ± 233 N）均显著提高（<0.01）。主要分析显示，CP-G 组的去脂体重增加（= 0.010）和脂肪量减少（= 0.023）明显高于 P-G 组。探索性分析显示，WP-G 与 CP-G 或 P-G 相比，去脂体重和脂肪量的变化无统计学差异。结论：与安慰剂相比，特定胶原蛋白肽补充剂与 RT 联合使用可显著增加去脂体重并减少脂肪量。RT 联合乳清蛋白对身体成分也有积极影响，但特定胶原蛋白肽给药后的效果更为明显。
