• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

特定胶原蛋白肽联合抗阻训练改善绝经前妇女身体成分和局部肌肉力量:一项随机对照试验。

Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial.

机构信息

Department for Nutrition, Institute for Sports and Sports Science, University of Freiburg, Schwarzwaldstraße 175, 79117 Freiburg, Germany.

出版信息

Nutrients. 2019 Apr 20;11(4):892. doi: 10.3390/nu11040892.

DOI:10.3390/nu11040892
PMID:31010031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6521629/
Abstract

The aim was to investigate the effects of resistance exercise combined with supplementation of specific collagen peptides (SCP) on body composition and muscle strength in premenopausal women. In a double-blind, placebo-controlled, randomized trial 77 premenopausal women completed a 12-week resistance training (3 day/week) and ingested 15 g of SCP or placebo on a daily basis. Changes in body composition were determined by bioelectrical impedance analysis (BIA) and muscular strength by isometric strength testing. The treatment group (TG) significantly increased ( < 0.001) their percentage of fat-free mass. Although the control group (CG) also showed a significant ( < 0.01) gain in fat-free mass from pre- to post-training, the increase in the TG was significantly higher in an RMANOVA analysis ( < 0.05). Regarding the change in percentage body fat, a significant decline was observed in both TG ( < 0.001) and CG ( < 0.01), with a significantly higher reduction in the TG ( < 0.05). Subjects receiving 15 g of collagen peptides daily also showed a significantly higher gain in hand-grip strength compared to those performing resistance training only ( < 0.05). In both groups, the gain in leg strength (TG = < 0.001; CG = < 0.01) was significant after 12 weeks with a more pronounced effect in the treatment group. In conclusion, resistance training in combination with supplementation of SCP induced a significantly higher increase in fat-free mass and hand-grip strength than resistance training and placebo supplementation. In addition, there was a significantly higher loss in fat mass and a more pronounced increase in leg strength in the treatment group compared to the control group.

摘要

目的

研究抗阻运动联合补充特定胶原蛋白肽(SCP)对绝经前妇女身体成分和肌肉力量的影响。在一项双盲、安慰剂对照、随机试验中,77 名绝经前妇女完成了 12 周的抗阻训练(每周 3 天),并每天摄入 15 克 SCP 或安慰剂。通过生物电阻抗分析(BIA)确定身体成分的变化,通过等长力量测试确定肌肉力量的变化。治疗组(TG)的去脂体重百分比显著增加(<0.001)。尽管对照组(CG)在训练前后也显示出显著的(<0.01)去脂体重增加,但在 RMANOVA 分析中,TG 的增加明显更高(<0.05)。关于体脂百分比的变化,TG(<0.001)和 CG(<0.01)均观察到显著下降,TG 的下降幅度明显更高(<0.05)。每天接受 15 克胶原蛋白肽的受试者的握力也比仅进行抗阻训练的受试者显著增加(<0.05)。在两组中,12 周后腿部力量的增加(TG = <0.001;CG = <0.01)均具有统计学意义,且治疗组的效果更为明显。结论:抗阻训练联合 SCP 补充可显著增加去脂体重和握力,效果优于抗阻训练和安慰剂补充。此外,与对照组相比,治疗组的体脂减少量显著增加,腿部力量增加更为明显。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9026/6521629/7ea366538133/nutrients-11-00892-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9026/6521629/e1e22877e775/nutrients-11-00892-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9026/6521629/789516362c8e/nutrients-11-00892-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9026/6521629/7ea366538133/nutrients-11-00892-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9026/6521629/e1e22877e775/nutrients-11-00892-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9026/6521629/789516362c8e/nutrients-11-00892-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9026/6521629/7ea366538133/nutrients-11-00892-g003.jpg

相似文献

1
Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial.特定胶原蛋白肽联合抗阻训练改善绝经前妇女身体成分和局部肌肉力量:一项随机对照试验。
Nutrients. 2019 Apr 20;11(4):892. doi: 10.3390/nu11040892.
2
Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial.补充胶原蛋白肽联合抗阻训练可改善老年肌肉减少症男性的身体成分并增强肌肉力量:一项随机对照试验。
Br J Nutr. 2015 Oct 28;114(8):1237-45. doi: 10.1017/S0007114515002810. Epub 2015 Sep 10.
3
Effect of calcium β-hydroxy-β-methylbutyrate (CaHMB) with and without resistance training in men and women 65+yrs: a randomized, double-blind pilot trial.65 岁及以上男性和女性中,补充钙 β-羟基-β-甲基丁酸(CaHMB)结合或不结合抗阻训练的效果:一项随机、双盲的初步试验。
Exp Gerontol. 2013 Nov;48(11):1303-10. doi: 10.1016/j.exger.2013.08.007. Epub 2013 Aug 24.
4
The effects of whey protein with or without carbohydrates on resistance training adaptations.含或不含碳水化合物的乳清蛋白对阻力训练适应性的影响。
J Int Soc Sports Nutr. 2015 Dec 16;12:48. doi: 10.1186/s12970-015-0109-4. eCollection 2015.
5
The Influence of Specific Bioactive Collagen Peptides on Body Composition and Muscle Strength in Middle-Aged, Untrained Men: A Randomized Controlled Trial.特定生物活性胶原蛋白肽对中年未经训练男性身体成分和肌肉力量的影响:一项随机对照试验。
Int J Environ Res Public Health. 2021 Apr 30;18(9):4837. doi: 10.3390/ijerph18094837.
6
Effects of 12 Weeks of Hypertrophy Resistance Exercise Training Combined with Collagen Peptide Supplementation on the Skeletal Muscle Proteome in Recreationally Active Men.12 周抗阻力量训练联合补充胶原蛋白肽对活跃男性骨骼肌蛋白质组的影响。
Nutrients. 2019 May 14;11(5):1072. doi: 10.3390/nu11051072.
7
Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.考察匙羹藤补充剂对肌肉力量和恢复的影响:一项随机对照试验。
J Int Soc Sports Nutr. 2015 Nov 25;12:43. doi: 10.1186/s12970-015-0104-9. eCollection 2015.
8
The effects of chronic betaine supplementation on body composition and performance in collegiate females: a double-blind, randomized, placebo controlled trial.慢性甜菜碱补充对大学生女性身体成分和表现的影响:一项双盲、随机、安慰剂对照试验。
J Int Soc Sports Nutr. 2018 Jul 31;15(1):37. doi: 10.1186/s12970-018-0243-x.
9
The effects of phosphatidic acid supplementation on strength, body composition, muscular endurance, power, agility, and vertical jump in resistance trained men.补充磷脂酸对进行抗阻训练男性的力量、身体成分、肌肉耐力、功率、敏捷性和垂直纵跳的影响。
J Int Soc Sports Nutr. 2016 Jun 2;13:24. doi: 10.1186/s12970-016-0135-x. eCollection 2016.
10
Effect of Bang® Pre-Workout Master Blaster® combined with four weeks of resistance training on lean body mass, maximal strength, mircoRNA expression, and serum IGF-1 in men: a randomized, double-blind, placebo-controlled trial.Bang® 预锻炼大师 Blaster® 联合四周抗阻训练对男性瘦体重、最大力量、微小 RNA 表达和血清 IGF-1 的影响:一项随机、双盲、安慰剂对照试验。
J Int Soc Sports Nutr. 2019 Nov 19;16(1):54. doi: 10.1186/s12970-019-0310-y.

引用本文的文献

1
The effects of regular training on spinal posture: a fitness and bodybuilding perspective.规律训练对脊柱姿势的影响:健身与健美视角
Front Physiol. 2025 Mar 5;16:1559150. doi: 10.3389/fphys.2025.1559150. eCollection 2025.
2
Advances in Molecular Function and Recombinant Expression of Human Collagen.人类胶原蛋白的分子功能与重组表达研究进展
Pharmaceuticals (Basel). 2025 Mar 18;18(3):430. doi: 10.3390/ph18030430.
3
The Effects of Type I Collagen Hydrolysate Supplementation on Bones, Muscles, and Joints: A Systematic Review.

本文引用的文献

1
Muscle and Bone Health in Postmenopausal Women: Role of Protein and Vitamin D Supplementation Combined with Exercise Training.绝经后妇女的肌肉和骨骼健康:蛋白质和维生素 D 补充与运动训练的作用。
Nutrients. 2018 Aug 16;10(8):1103. doi: 10.3390/nu10081103.
2
Effect of whey protein supplementation on body composition changes in women: a systematic review and meta-analysis.乳清蛋白补充对女性身体成分变化的影响:系统评价和荟萃分析。
Nutr Rev. 2018 Jul 1;76(7):539-551. doi: 10.1093/nutrit/nuy017.
3
Differences in handgrip strength protocols to identify sarcopenia and frailty - a systematic review.
补充I型胶原蛋白水解物对骨骼、肌肉和关节的影响:一项系统综述。
Orthop Rev (Pavia). 2025 Feb 19;17:129086. doi: 10.52965/001c.129086. eCollection 2025.
4
Nutritional Interventions to Attenuate Quadriceps Muscle Deficits following Anterior Cruciate Ligament Injury and Reconstruction.营养干预减轻前交叉韧带损伤与重建后股四头肌功能障碍
Sports Med. 2025 Mar;55(3):569-596. doi: 10.1007/s40279-025-02174-w. Epub 2025 Jan 24.
5
Obesity and Metabolic Disease Impair the Anabolic Response to Protein Supplementation and Resistance Exercise: A Retrospective Analysis of a Randomized Clinical Trial with Implications for Aging, Sarcopenic Obesity, and Weight Management.肥胖与代谢性疾病会损害对蛋白质补充和抗阻运动的合成代谢反应:一项随机临床试验的回顾性分析,对衰老、肌少症肥胖和体重管理具有启示意义。
Nutrients. 2024 Dec 23;16(24):4407. doi: 10.3390/nu16244407.
6
Anti-Obesity Effects of a Collagen with Low Digestibility and High Swelling Capacity: A Human Randomized Control Trial.低消化率和高溶胀能力胶原蛋白的抗肥胖效果:一项人体随机对照试验。
Nutrients. 2024 Oct 19;16(20):3550. doi: 10.3390/nu16203550.
7
Impact of Collagen Peptide Supplementation in Combination with Long-Term Physical Training on Strength, Musculotendinous Remodeling, Functional Recovery, and Body Composition in Healthy Adults: A Systematic Review with Meta-analysis.胶原肽补充联合长期身体训练对健康成年人的力量、肌肉肌腱重塑、功能恢复和身体成分的影响:系统评价和荟萃分析。
Sports Med. 2024 Nov;54(11):2865-2888. doi: 10.1007/s40279-024-02079-0. Epub 2024 Jul 26.
8
Influence of specific collagen peptides and 12-week concurrent training on recovery-related biomechanical characteristics following exercise-induced muscle damage-A randomized controlled trial.特定胶原蛋白肽与12周同步训练对运动诱导的肌肉损伤后恢复相关生物力学特征的影响——一项随机对照试验
Front Nutr. 2023 Nov 16;10:1266056. doi: 10.3389/fnut.2023.1266056. eCollection 2023.
9
Preventive Effects of Collagen-Derived Dipeptide Prolyl-Hydroxyproline against Dexamethasone-Induced Muscle Atrophy in Mouse C2C12 Skeletal Myotubes.胶原衍生二肽脯氨酰-羟脯氨酸对地塞米松诱导的 C2C12 骨骼肌肌管萎缩的预防作用。
Biomolecules. 2023 Nov 5;13(11):1617. doi: 10.3390/biom13111617.
10
Low-Molecular Collagen Peptide Supplementation and Body Fat Mass in Adults Aged ≥ 50 Years: A Randomized, Double-Blind, Placebo-Controlled Trial.低分子胶原蛋白肽补充剂与≥50岁成年人的体脂肪量:一项随机、双盲、安慰剂对照试验
Clin Nutr Res. 2023 Oct 31;12(4):245-256. doi: 10.7762/cnr.2023.12.4.245. eCollection 2023 Oct.
用于识别肌肉减少症和虚弱的握力测试方案差异——一项系统评价
BMC Geriatr. 2017 Oct 16;17(1):238. doi: 10.1186/s12877-017-0625-y.
4
A systematic review, meta-analysis and meta-regression of the effect of protein supplementation on resistance training-induced gains in muscle mass and strength in healthy adults.蛋白质补充对健康成年人抗阻训练引起的肌肉量和力量增加影响的系统评价、荟萃分析和荟萃回归
Br J Sports Med. 2018 Mar;52(6):376-384. doi: 10.1136/bjsports-2017-097608. Epub 2017 Jul 11.
5
Glycine metabolism in skeletal muscle: implications for metabolic homeostasis.骨骼肌中的甘氨酸代谢:对代谢稳态的影响。
Curr Opin Clin Nutr Metab Care. 2017 Jul;20(4):237-242. doi: 10.1097/MCO.0000000000000383.
6
Quantification of whole-body and segmental skeletal muscle mass using phase-sensitive 8-electrode medical bioelectrical impedance devices.使用相敏 8 电极医疗生物电阻抗设备定量全身和节段性骨骼肌量。
Eur J Clin Nutr. 2017 Sep;71(9):1061-1067. doi: 10.1038/ejcn.2017.27. Epub 2017 Mar 22.
7
Amelioration of estrogen deficiency-induced obesity by collagen hydrolysate.胶原蛋白水解物改善雌激素缺乏诱导的肥胖。
Int J Med Sci. 2016 Oct 19;13(11):853-857. doi: 10.7150/ijms.16706. eCollection 2016.
8
Glycine Regulates Protein Turnover by Activating Protein Kinase B/Mammalian Target of Rapamycin and by Inhibiting MuRF1 and Atrogin-1 Gene Expression in C2C12 Myoblasts.甘氨酸通过激活蛋白激酶B/雷帕霉素哺乳动物靶蛋白以及抑制C2C12成肌细胞中MuRF1和Atrogin-1基因表达来调节蛋白质周转。
J Nutr. 2016 Dec;146(12):2461-2467. doi: 10.3945/jn.116.231266. Epub 2016 Oct 26.
9
The collagen derived dipeptide hydroxyprolyl-glycine promotes C2C12 myoblast differentiation and myotube hypertrophy.胶原蛋白衍生的二肽羟脯氨酰甘氨酸可促进C2C12成肌细胞分化和肌管肥大。
Biochem Biophys Res Commun. 2016 Sep 23;478(3):1292-7. doi: 10.1016/j.bbrc.2016.08.114. Epub 2016 Aug 21.
10
Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS.甘氨酸可增强肌肉蛋白质量,这与维持仔猪在受到脂多糖攻击时的Akt-mTOR-FOXO1信号传导以及抑制TLR4和NOD2信号传导有关。
Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R365-73. doi: 10.1152/ajpregu.00043.2016. Epub 2016 May 25.