使用275纳米紫外线C发光二极管通过球形辐照箱灭活严重急性呼吸综合征冠状病毒2：设计、特性表征与验证
Inactivating SARS-CoV-2 Using 275 nm UV-C LEDs through a Spherical Irradiation Box: Design, Characterization and Validation.
作者信息
Trivellin Nicola, Buffolo Matteo, Onelia Francesco, Pizzolato Alberto, Barbato Marco, Orlandi Viviana Teresa, Del Vecchio Claudia, Dughiero Fabrizio, Zanoni Enrico, Meneghesso Gaudenzio, Crisanti Andrea, Meneghini Matteo
机构信息
Department of Industrial Engineering, University of Padova, Via Gradenigo 6A, 35131 Padova, Italy.
Department of Information Engineering, University of Padova, Via Gradenigo 6B, 35131 Padova, Italy.
出版信息
Materials (Basel). 2021 Apr 29;14(9):2315. doi: 10.3390/ma14092315.
We report on the design, characterization and validation of a spherical irradiation system for inactivating SARS-CoV-2, based on UV-C 275 nm LEDs. The system is designed to maximize irradiation intensity and uniformity and can be used for irradiating a volume of 18 L. To this aim: (i) several commercially available LEDs have been acquired and analyzed; (ii) a complete optical study has been carried out in order to optimize the efficacy of the system; (iii) the resulting prototype has been characterized optically and tested for the inactivation of SARS-CoV-2 for different exposure times, doses and surface types; (iv) the result achieved and the efficacy of the prototype have been compared with similar devices based on different technologies. Results indicate that a 99.9% inactivation can be reached after 1 min of treatment with a dose of 83.1 J/m.
我们报告了一种基于275 nm紫外线发光二极管（LED）的用于灭活新型冠状病毒（SARS-CoV-2）的球形辐照系统的设计、特性表征及验证。该系统旨在使辐照强度和均匀性最大化，可用于辐照18升的体积。为此：（i）已采购并分析了几种市售LED；（ii）进行了完整的光学研究以优化系统效能；（iii）对所得原型进行了光学特性表征，并针对不同的暴露时间、剂量和表面类型测试了其对SARS-CoV-2的灭活效果；（iv）将所取得的结果及原型的效能与基于不同技术的类似设备进行了比较。结果表明，在剂量为83.1 J/m²的情况下处理1分钟后，灭活率可达99.9%。
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