Perry Jamie L, Kuehn David P, Sutton Bradley P, Goldwasser Michael S, Jerez Alex D
Department of Communication Sciences and Disorders, Illinois State University, Normal, Illinois, USA.
J Craniofac Surg. 2011 Mar;22(2):499-503. doi: 10.1097/SCS.0b013e3182087378.
The current study was designed to obtain qualitative and quantitative information of the velopharyngeal mechanism and craniometric dimensions in infants born with a normal mechanism and in infants with an unrepaired cleft palate.
Clinical magnetic resonance imaging data were obtained from the medical charts of 4 infants (2 with cleft lip and palate and 2 without) between the ages of 8 and 9 months. Craniometric measures and levator veli palatini muscle morphology were analyzed using visualization modeling software. Both raw measures and measures normalized by head circumference were examined.
Patients 1 and 2 demonstrated normal velopharyngeal anatomy and a similar distance between levator muscle origins (38.9-40.7 mm), sagittal angles of origin (56-57 degrees), and levator muscle bundle lengths (28.4-30.7 mm). Patients with an unrepaired cleft palate displayed smaller oblique coronal angles of origins (58-62 degrees) compared with patients without cleft palate (62-67 degrees). Patients without cleft palate showed a steeper muscle (56-57 degrees) compared with patients without cleft palate (66-67 degrees). The basion-sella-nasion angle, hard palate length, and hard palate width measurements are related systematically to head circumference in this patient group.
Results from the current study are in agreement with previous studies demonstrating variations across patients with cleft palate particularly in the muscle bundle lengths, distance between muscle origins, velar thickness, and velar length. Longitudinal studies are needed to determine how levator muscle and craniometric dimensions vary between those with and without cleft palate. A larger sample size is necessary to provide statistical analysis.
本研究旨在获取腭咽机制正常的婴儿以及未修复腭裂婴儿的腭咽机制和颅骨测量尺寸的定性和定量信息。
从4名年龄在8至9个月的婴儿（2名唇腭裂婴儿和2名非唇腭裂婴儿）的病历中获取临床磁共振成像数据。使用可视化建模软件分析颅骨测量数据和腭帆提肌形态。对原始测量数据和按头围标准化的测量数据均进行了检查。
患者1和患者2表现出正常的腭咽解剖结构，腭帆提肌起点之间的距离（38.9 - 40.7毫米）、起点矢状角（56 - 57度）和腭帆提肌束长度（28.4 - 30.7毫米）相似。与非腭裂患者（62 - 67度）相比，未修复腭裂的患者起点斜冠状角较小（58 - 62度）。与非腭裂患者（66 - 67度）相比，腭裂患者的肌肉角度更陡（56 - 57度）。在该患者组中，前囟 - 蝶鞍 - 鼻根角、硬腭长度和硬腭宽度测量值与头围系统相关。
本研究结果与先前的研究一致，表明腭裂患者之间存在差异，特别是在肌束长度、肌肉起点之间的距离、腭部厚度和腭部长度方面。需要进行纵向研究以确定腭裂患者和非腭裂患者之间腭帆提肌和颅骨测量尺寸如何变化。需要更大的样本量来进行统计分析。
