• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

心力衰竭住院治疗:统一 30 年后东德和西德仍存在显著差异。

Hospitalizations for heart failure: still major differences between East and West Germany 30 years after reunification.

机构信息

Department of Internal Medicine B, University Medicine Greifswald, Ferdinand-Sauerbruch-Straße, Greifswald, Germany.

DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.

出版信息

ESC Heart Fail. 2021 Aug;8(4):2546-2555. doi: 10.1002/ehf2.13407. Epub 2021 May 4.

DOI:10.1002/ehf2.13407
PMID:33949148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8318397/
Abstract

AIMS

Heart failure (HF) is the most common primary inpatient diagnosis in Germany. We examined temporal trends of HF hospitalization within Germany focusing on regional differences.

METHODS AND RESULTS

We analysed aggregated data of more than 320 million hospitalizations in Germany from 2000 to 2017. Temporal trends of HF-related parameters were analysed, focusing on regional differences between the federal states. The absolute number of HF-related hospitalizations throughout Germany increased continuously and almost doubled (from 239 694 to 464 724 cases, +94%) with the relative increase being higher in East Germany compared with West Germany (119% vs. 88%). These regional differences persisted after age standardization with 609 and 490 cases per 100 000 population, respectively. The length of stay decreased continuously across Germany (from 14.3 to 10.2 days; -29%), while the total number of HF-related hospital days increased by 51% in East Germany and 35% in West Germany. In 2017, HF remained the leading cause of in-hospital death (8.9% of all cases), with a markedly higher rate in East vs. West Germany (65 vs. 43 deaths per 100 000 population).

CONCLUSIONS

Heart failure remains the most common cause of hospitalization and in-hospital death throughout Germany. The increase in HF-related morbidity and mortality was much higher in East Germany compared with West Germany during the observation period. A more detailed understanding of these striking disparities 30 years after the German reunification requires further investigations. There is an urgent need for action with regard to stronger control of risk factors and improvement of both chronic HF management and healthcare structures.

摘要

目的

心力衰竭(HF)是德国最常见的主要住院诊断。我们研究了德国心力衰竭住院治疗的时间趋势,重点关注区域差异。

方法和结果

我们分析了 2000 年至 2017 年德国超过 3.2 亿例住院治疗的汇总数据。分析了与 HF 相关的参数的时间趋势,重点关注联邦州之间的区域差异。德国全国与 HF 相关的住院治疗绝对数量持续增加,几乎翻了一番(从 239694 例增加到 464724 例,增加了 94%),东德的相对增加高于西德(119%比 88%)。这些区域差异在年龄标准化后仍然存在,分别为每 10 万人中有 609 例和 490 例。德国各地的住院时间持续缩短(从 14.3 天减少到 10.2 天,减少了 29%),而与 HF 相关的住院天数在东德增加了 51%,在西德增加了 35%。2017 年,HF 仍然是住院死亡的主要原因(占所有病例的 8.9%),东德的死亡率明显高于西德(每 10 万人中有 65 例和 43 例死亡)。

结论

心力衰竭仍然是德国最常见的住院和院内死亡原因。在观察期间,东德与 HF 相关的发病率和死亡率的增加明显高于西德。在德国统一 30 年后,需要进一步调查这些惊人差异的更详细情况。需要采取行动,加强危险因素的控制,改善慢性心力衰竭的管理和医疗保健结构。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22a5/8318397/0c54e1434aa8/EHF2-8-2546-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22a5/8318397/30bb85ae33ac/EHF2-8-2546-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22a5/8318397/d688bedbd49b/EHF2-8-2546-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22a5/8318397/0c54e1434aa8/EHF2-8-2546-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22a5/8318397/30bb85ae33ac/EHF2-8-2546-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22a5/8318397/d688bedbd49b/EHF2-8-2546-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22a5/8318397/0c54e1434aa8/EHF2-8-2546-g002.jpg

相似文献

1
Hospitalizations for heart failure: still major differences between East and West Germany 30 years after reunification.心力衰竭住院治疗:统一 30 年后东德和西德仍存在显著差异。
ESC Heart Fail. 2021 Aug;8(4):2546-2555. doi: 10.1002/ehf2.13407. Epub 2021 May 4.
2
Heart failure epidemiology 2000-2013: insights from the German Federal Health Monitoring System.心力衰竭流行病学 2000-2013:来自德国联邦健康监测系统的见解。
Eur J Heart Fail. 2016 Aug;18(8):1009-18. doi: 10.1002/ejhf.567. Epub 2016 Jun 1.
3
Sex-specific differences drive temporal trends and outcomes of patients hospitalized for heart failure in Germany.性别特异性差异导致德国心力衰竭住院患者的时间趋势和结局不同。
Prog Cardiovasc Dis. 2020 Sep-Oct;63(5):591-598. doi: 10.1016/j.pcad.2020.03.013. Epub 2020 Mar 26.
4
Trends in hospitalization for congestive heart failure, 1996-2009.1996 - 2009年充血性心力衰竭的住院趋势
Clin Cardiol. 2017 Feb;40(2):109-119. doi: 10.1002/clc.22638. Epub 2016 Nov 12.
5
[30 years of German unification: achievements and remaining differences in mortality trends by age and cause of death].[德国统一30年:按年龄和死因划分的死亡率趋势的成就与尚存差异]
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2021 Apr;64(4):481-490. doi: 10.1007/s00103-021-03299-9. Epub 2021 Mar 25.
6
Trends in hospitalizations for heart failure, acute myocardial infarction, and stroke in the United States from 2004 to 2018.2004 年至 2018 年美国心力衰竭、急性心肌梗死和中风住院治疗趋势。
Am Heart J. 2022 Jan;243:103-109. doi: 10.1016/j.ahj.2021.09.009. Epub 2021 Sep 25.
7
Methamphetamine-Associated Heart Failure Hospitalizations Across the United States: Geographic and Social Disparities.美国各地与甲基苯丙胺相关的心力衰竭住院情况:地理和社会差异
J Am Heart Assoc. 2021 Aug 17;10(16):e018370. doi: 10.1161/JAHA.120.018370. Epub 2021 Aug 7.
8
Rural-Urban Disparities in Heart Failure and Acute Myocardial Infarction Hospitalizations.农村-城市心力衰竭和急性心肌梗死住院的差异。
Am J Cardiol. 2022 Jul 15;175:164-169. doi: 10.1016/j.amjcard.2022.04.014. Epub 2022 May 14.
9
In-hospital care in acute heart failure during the COVID-19 pandemic: insights from the German-wide Helios hospital network.COVID-19 大流行期间急性心力衰竭的院内治疗:来自德国 Helios 医院网络的见解。
Eur J Heart Fail. 2020 Dec;22(12):2190-2201. doi: 10.1002/ejhf.2044. Epub 2020 Dec 2.
10
Trends in alcohol-related mortality in East and West Germany, 1980-2014: age, period and cohort variations.1980-2014 年东德和西德与酒精相关的死亡率趋势:年龄、时期和队列变化。
Addiction. 2018 May;113(5):836-844. doi: 10.1111/add.14152. Epub 2018 Feb 9.

引用本文的文献

1
Lower ambulatory care availability and greater hospital capacity are associated with higher hospital case volumes.门诊护理可及性较低和医院容量较大与更高的医院病例量相关。
Res Health Serv Reg. 2025 Jun 10;4(1):7. doi: 10.1007/s43999-025-00066-0.
2
Vocal biomarkers in heart failure-design, rationale and baseline characteristics of the AHF-Voice study.心力衰竭中的声音生物标志物——急性心力衰竭声音研究(AHF-Voice study)的设计、原理及基线特征
Front Digit Health. 2025 May 2;7:1548600. doi: 10.3389/fdgth.2025.1548600. eCollection 2025.
3
Poor communication impairs optimal care of patients with heart failure and erectile dysfunction.

本文引用的文献

1
Temporal trends and predictors of inhospital death in patients hospitalised for heart failure in Germany.德国因心力衰竭住院患者院内死亡的时间趋势和预测因素。
Eur J Prev Cardiol. 2021 Aug 9;28(9):990-997. doi: 10.1177/2047487320936020. Epub 2020 Jun 30.
2
The Treatment of Heart Failure with Reduced Ejection Fraction.射血分数降低型心力衰竭的治疗。
Dtsch Arztebl Int. 2020 May 22;117(21):376-386. doi: 10.3238/arztebl.2020.0376.
3
Cardiovascular Health Score and Lifetime Risk of Cardiovascular Disease: The Cardiovascular Lifetime Risk Pooling Project.
沟通不畅会损害心力衰竭和勃起功能障碍患者的最佳治疗效果。
ESC Heart Fail. 2025 Jun;12(3):1932-1941. doi: 10.1002/ehf2.15201. Epub 2025 Jan 19.
4
The Cold War in pharmacology: a bibliometric analysis of Berlin's contributions to Naunyn‑Schmiedeberg's Archives of Pharmacology (1947-1974).药理学冷战:柏林对瑙文-施密德贝格药理学档案的贡献的文献计量分析(1947-1974)。
Naunyn Schmiedebergs Arch Pharmacol. 2024 Oct;397(10):7963-7980. doi: 10.1007/s00210-024-03115-6. Epub 2024 May 17.
5
Real-world characteristics and use patterns of patients treated with vericiguat: A nationwide longitudinal cohort study in Germany.在德国开展的一项全国性纵向队列研究:维立西呱治疗患者的真实世界特征和使用模式。
Eur J Clin Pharmacol. 2024 Jun;80(6):931-940. doi: 10.1007/s00228-024-03654-0. Epub 2024 Mar 12.
6
Impact of the COVID-19 pandemic on implementation of novel guideline-directed medical therapies for heart failure in Germany: a nationwide retrospective analysis.新冠疫情对德国心力衰竭新型指南导向药物治疗实施情况的影响:一项全国性回顾性分析
Lancet Reg Health Eur. 2023 Nov 7;35:100778. doi: 10.1016/j.lanepe.2023.100778. eCollection 2023 Dec.
7
Epidemiology of cardiac amyloidosis in Germany: a retrospective analysis from 2009 to 2018.德国心脏淀粉样变性的流行病学:2009 年至 2018 年的回顾性分析。
Clin Res Cardiol. 2023 Mar;112(3):401-408. doi: 10.1007/s00392-022-02114-y. Epub 2022 Oct 14.
8
A practical approach to the guideline-directed pharmacological treatment of heart failure with reduced ejection fraction.射血分数降低型心力衰竭的指南导向药物治疗的实用方法。
ESC Heart Fail. 2023 Feb;10(1):24-31. doi: 10.1002/ehf2.14197. Epub 2022 Oct 13.
9
Sacubitril/valsartan in heart failure: efficacy and safety in and outside clinical trials.沙库巴曲缬沙坦在心力衰竭中的疗效和安全性:临床试验内外。
ESC Heart Fail. 2022 Dec;9(6):3737-3750. doi: 10.1002/ehf2.14097. Epub 2022 Aug 3.
10
Comorbidities in heart failure with preserved ejection fraction.射血分数保留的心力衰竭中的合并症。
Herz. 2022 Aug;47(4):301-307. doi: 10.1007/s00059-022-05123-9. Epub 2022 Jun 8.
心血管健康评分与心血管疾病的终生风险:心血管终生风险汇总项目
Circ Cardiovasc Qual Outcomes. 2020 Jul;13(7):e006450. doi: 10.1161/CIRCOUTCOMES.119.006450. Epub 2020 Jun 30.
4
Sex-specific differences drive temporal trends and outcomes of patients hospitalized for heart failure in Germany.性别特异性差异导致德国心力衰竭住院患者的时间趋势和结局不同。
Prog Cardiovasc Dis. 2020 Sep-Oct;63(5):591-598. doi: 10.1016/j.pcad.2020.03.013. Epub 2020 Mar 26.
5
Survival of patients with chronic heart failure in the community: a systematic review and meta-analysis.社区慢性心力衰竭患者的生存状况:系统评价和荟萃分析。
Eur J Heart Fail. 2019 Nov;21(11):1306-1325. doi: 10.1002/ejhf.1594. Epub 2019 Sep 16.
6
Clinical practice update on heart failure 2019: pharmacotherapy, procedures, devices and patient management. An expert consensus meeting report of the Heart Failure Association of the European Society of Cardiology.2019 年心力衰竭临床实践更新:药物治疗、程序、设备和患者管理。欧洲心脏病学会心力衰竭协会专家共识会议报告。
Eur J Heart Fail. 2019 Oct;21(10):1169-1186. doi: 10.1002/ejhf.1531. Epub 2019 Aug 30.
7
Prevalence, Mortality, and Indicators of Health Care Supply-Association Analysis of Cardiovascular Diseases in Germany.德国心血管疾病的患病率、死亡率及医疗保健供应指标关联分析
Front Cardiovasc Med. 2018 Oct 30;5:158. doi: 10.3389/fcvm.2018.00158. eCollection 2018.
8
Efficacy of telemedical interventional management in patients with heart failure (TIM-HF2): a randomised, controlled, parallel-group, unmasked trial.远程医疗介入管理对心力衰竭患者的疗效(TIM-HF2):一项随机、对照、平行组、非盲试验。
Lancet. 2018 Sep 22;392(10152):1047-1057. doi: 10.1016/S0140-6736(18)31880-4. Epub 2018 Aug 25.
9
Medical Therapy for Heart Failure With Reduced Ejection Fraction: The CHAMP-HF Registry.射血分数降低的心力衰竭的药物治疗:CHAMP-HF 注册研究。
J Am Coll Cardiol. 2018 Jul 24;72(4):351-366. doi: 10.1016/j.jacc.2018.04.070.
10
Epidemiology of heart failure with preserved ejection fraction.射血分数保留型心力衰竭的流行病学。
Nat Rev Cardiol. 2017 Oct;14(10):591-602. doi: 10.1038/nrcardio.2017.65. Epub 2017 May 11.