State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, Jiangsu 210023, China.
Analyst. 2021 May 4;146(9):2807-2817. doi: 10.1039/d1an00077b.
Self-assembled nanomaterials (SANs) exhibit designable biofunctions owing to their tunable nanostructures and modifiable surface. Various constituent units and multi-dimensional structures of SANs provide unlimited possibilities for numerous applications. This review emphasizes the recent development of SANs in the fields of biosensing, bioimaging, and nano-drug engineering. The unit type, design concepts, material advantages, assembly driving force, nanostructure effects, drug loading performance, etc. are discussed and summarized. Finally, we briefly summarize how to assemble unique nanomaterials and point out the key challenges in this field.
自组装纳米材料（SANs）由于其可调的纳米结构和可修饰的表面而表现出可设计的生物功能。SANs 的各种组成单元和多维结构为众多应用提供了无限的可能性。本综述强调了 SANs 在生物传感、生物成像和纳米药物工程领域的最新发展。讨论和总结了单元类型、设计理念、材料优势、组装驱动力、纳米结构效应、药物装载性能等。最后，我们简要总结了如何组装独特的纳米材料，并指出了该领域的关键挑战。
