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癌症治疗后的继发性淋巴水肿。

Secondary lymphedema from cancer therapy.

机构信息

TCU and UNTHSC School of Medicine, Fort Worth, TX, USA.

California Pacific Medical Center Cancer Center, CPMC, San Francisco, CA, USA.

出版信息

Clin Exp Metastasis. 2022 Feb;39(1):239-247. doi: 10.1007/s10585-021-10096-w. Epub 2021 May 5.

DOI:10.1007/s10585-021-10096-w
PMID:33950413
Abstract

This manuscript is a summary of findings focusing on various aspects of secondary lymphedema specifically as a sequelae of treatment for cancer. The topic was addressed at a session held during the 8th International Congress on Cancer Metastasis that was unique a for the inclusion of patients with lymphedema and therapists joining physicians, healthcare professionals, and researchers in an effort to give an overview of secondary lymphedema following cancer therapy as well as highlighting the unknowns in the field. Lymphedema is defined and both diagnosis and incidence of cancer-related lymphedema are explored. Further, exploration of imaging options for lymphedema and information on the genetic research for patients with cancer-related secondary lymphedema are presented. Patient education and early detection methods are then explored followed by conservative treatment. Finally, an examination of surgical treatment methods available for patients with lymphedema is covered. Overall, this manuscript presents valuable information and updates for those not familiar with incidence, diagnosis, early detection, and rehabilitation of patients with cancer-related secondary lymphedema.

摘要

这篇手稿是一份研究结果的总结,重点关注继发于癌症治疗的继发性淋巴水肿的各个方面。该主题在第 8 届癌症转移国际大会期间的一个会议上进行了讨论,该会议的独特之处在于包括了淋巴水肿患者以及治疗师,他们与医生、医疗保健专业人员和研究人员一起努力,全面概述癌症治疗后的继发性淋巴水肿,并强调该领域的未知因素。淋巴水肿的定义以及癌症相关淋巴水肿的诊断和发病率都进行了探讨。此外,还探讨了淋巴水肿的影像学选择以及癌症相关继发性淋巴水肿患者的遗传研究信息。然后探讨了患者教育和早期检测方法,接着是保守治疗。最后,检查了可供淋巴水肿患者使用的手术治疗方法。总的来说,对于不熟悉癌症相关继发性淋巴水肿的发病率、诊断、早期检测和康复的人来说,这篇手稿提供了有价值的信息和更新。

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本文引用的文献

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Characterization of mutations associated with primary lymphedema.原发性淋巴水肿相关突变的特征。
Sci Transl Med. 2020 Sep 9;12(560). doi: 10.1126/scitranslmed.aax8013.
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Update and audit of the St George's classification algorithm of primary lymphatic anomalies: a clinical and molecular approach to diagnosis.原发性淋巴异常的圣乔治分类算法的更新和审核:一种临床和分子诊断方法。
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妇科癌症患者的下肢淋巴水肿:德语版妇科癌症淋巴水肿问卷(GCLQ)的验证及淋巴水肿实际治疗情况调查
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Introduction: Novel Frontiers in Cancer Metastasis.引言:癌症转移的新前沿
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