单剂量亚胺培南-西司他丁治疗单纯性淋病。
Treatment of uncomplicated gonorrhea with single-dose imipenem-cilastatin.
作者信息
Verdon M S, Judson F N, Ehret J M, Root C J, Hook E W, McCormack W M, Frances C A, Draft K, Shands J W, Handsfield H H
机构信息
Department of Medicine, University of Washington School of Medicine, Seattle 98104.
出版信息
Antimicrob Agents Chemother. 1988 May;32(5):773-4. doi: 10.1128/AAC.32.5.773.
Abstract
Single 500-mg intramuscular doses of imipenem-cilastatin cured 116 (95%) of 122 men and 9 of 9 women with uncomplicated gonorrhea due to beta-lactamase-negative Neisseria gonorrhoeae. Most co-existing Chlamydia trachomatis infections persisted. Imipenem-cilastatin is effective for uncomplicated gonorrhea in men but has no advantages over other available regimens.
摘要
单次肌内注射500毫克亚胺培南-西司他丁，治愈了122例由β-内酰胺酶阴性淋病奈瑟菌引起的单纯性淋病男性患者中的116例（95%）以及9例女性患者中的9例。大多数同时存在的沙眼衣原体感染依然存在。亚胺培南-西司他丁对男性单纯性淋病有效，但与其他可用治疗方案相比并无优势。
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