单剂量亚胺培南-西司他丁治疗单纯性淋病。
Treatment of uncomplicated gonorrhea with single-dose imipenem-cilastatin.
作者信息
Verdon M S, Judson F N, Ehret J M, Root C J, Hook E W, McCormack W M, Frances C A, Draft K, Shands J W, Handsfield H H
机构信息
Department of Medicine, University of Washington School of Medicine, Seattle 98104.
出版信息
Antimicrob Agents Chemother. 1988 May;32(5):773-4. doi: 10.1128/AAC.32.5.773.
Abstract
Single 500-mg intramuscular doses of imipenem-cilastatin cured 116 (95%) of 122 men and 9 of 9 women with uncomplicated gonorrhea due to beta-lactamase-negative Neisseria gonorrhoeae. Most co-existing Chlamydia trachomatis infections persisted. Imipenem-cilastatin is effective for uncomplicated gonorrhea in men but has no advantages over other available regimens.
摘要
单次肌内注射500毫克亚胺培南-西司他丁，治愈了122例由β-内酰胺酶阴性淋病奈瑟菌引起的单纯性淋病男性患者中的116例（95%）以及9例女性患者中的9例。大多数同时存在的沙眼衣原体感染依然存在。亚胺培南-西司他丁对男性单纯性淋病有效，但与其他可用治疗方案相比并无优势。
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本文引用的文献
1
Ampicillin resistance in Haemophilus influenzae as determined by a rapid test for beta-lactamase production.
Antimicrob Agents Chemother. 1974 Nov;6(5):653-4. doi: 10.1128/AAC.6.5.653.
2
Microtest procedure for isolation of Chlamydia trachomatis.
J Clin Microbiol. 1981 Jun;13(6):1036-9. doi: 10.1128/jcm.13.6.1036-1039.1981.
3
In vitro susceptibility and cross-resistance of South African isolates of Neisseria gonorrhoeae to 14 antimicrobial agents.
Antimicrob Agents Chemother. 1982 Oct;22(4):598-603. doi: 10.1128/AAC.22.4.598.
4
Epidemiology of penicillinase-producing Neisseria gonorrhoeae infections: analysis by auxotyping and serogrouping.
N Engl J Med. 1982 Apr 22;306(16):950-4. doi: 10.1056/NEJM198204223061602.
5
Thienamycin: development of imipenen-cilastatin.
J Antimicrob Chemother. 1983 Dec;12 Suppl D:1-35. doi: 10.1093/jac/12.suppl_d.1.
6
Penicillinase-producing Neisseria gonorrhoeae--a retrospective.
N Engl J Med. 1982 Aug 12;307(7):438-9. doi: 10.1056/NEJM198208123070712.
7
Detection of Chlamydia trachomatis inclusions in Mccoy cell cultures with fluorescein-conjugated monoclonal antibodies.
J Clin Microbiol. 1983 Apr;17(4):666-8. doi: 10.1128/jcm.17.4.666-668.1983.
8
Single doses of methacycline and doxycycline for gonorrhea: a cooperative study of the frequency and cause of treatment failure.
J Infect Dis. 1973 Apr;127(4):461-6. doi: 10.1093/infdis/127.4.461.
9
Gonococcal infections.
Ann Intern Med. 1985 Feb;102(2):229-43. doi: 10.7326/0003-4819-102-2-229.
10
A community-based outbreak of infection with penicillin-resistant Neisseria gonorrhoeae not producing penicillinase (chromosomally mediated resistance).
N Engl J Med. 1985 Sep 5;313(10):607-11. doi: 10.1056/NEJM198509053131004.
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