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SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis.SARS-CoV-2、SARS-CoV 和 MERS-CoV 的病毒载量动态、病毒脱落持续时间和传染性:系统评价和荟萃分析。
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Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.ChAdOx1 nCoV-19 疫苗(阿斯利康)对 SARS-CoV-2 的安全性和有效性:巴西、南非和英国四项随机对照试验的中期分析。
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Covid-19: Oxford vaccine could be 59% effective against asymptomatic infections, analysis shows.新冠疫情:分析显示,牛津疫苗对无症状感染的有效性可能达59%。
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What's next for COVID-19 apps? Governance and oversight.新冠病毒应用程序的下一步是什么?治理与监督。
Science. 2020 Nov 13;370(6518):760-762. doi: 10.1126/science.abd9006.
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Superspreading events in the transmission dynamics of SARS-CoV-2: Opportunities for interventions and control.SARS-CoV-2 传播动力学中的超级传播事件:干预和控制的机会。
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Slovakia to test all adults for SARS-CoV-2.斯洛伐克将对所有成年人进行新冠病毒检测。
Lancet. 2020 Oct 31;396(10260):1386-1387. doi: 10.1016/S0140-6736(20)32261-3.
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Excess deaths from COVID-19 correlate with age and socio-economic status. A database study in the Stockholm region.COVID-19 导致的超额死亡与年龄和社会经济地位相关。斯德哥尔摩地区的数据库研究。
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Rethinking Covid-19 Test Sensitivity - A Strategy for Containment.重新思考新冠病毒检测敏感性——一种遏制策略。
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Challenges and Controversies to Testing for COVID-19.新冠病毒检测面临的挑战和争议。
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管理 COVID-19 大流行中的伦理问题。

Ethical issues in managing the COVID-19 pandemic.

机构信息

Ghent University Hospital, Gent, Belgium.

Department of Public Health and Primary Care, Ghent University, Gent, Belgium.

出版信息

Bioethics. 2021 Jul;35(6):581-588. doi: 10.1111/bioe.12877. Epub 2021 May 5.

DOI:10.1111/bioe.12877
PMID:33951206
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8239940/
Abstract

The COVID-19 pandemic has had an immense and worldwide impact. In light of future pandemics or subsequent waves of COVID-19 it is crucial to focus on the ethical issues that were and still are raised in this COVID-19 crisis. In this paper, we look at issues that are raised in the testing and tracing of patients with COVID-19. We do this by highlighting and expanding on an approach suggested by Fineberg that could serve as a public health approach. In this way, we highlight several ethical issues. As regards testing, questions are raised such as whether it is ethical to use less reliable tests in order to increase testing capacity or minimize harm for patients. Another issue is how wide testing should be and whether selective testing is in accordance with principles of social justice. Patients who have recovered from COVID-19 might have some degree of immunity but attributing certain 'immunopriviliges' raises ethical questions. The use of various tracing methodologies (mobile apps or databases and trained tracers) raised evident questions of social justice and privacy. We argue why it is key to always uphold a test of proportionality where a fair balance must be sought.

摘要

COVID-19 大流行产生了广泛而深远的全球性影响。鉴于未来可能发生的大流行或 COVID-19 的后续浪潮,关注在此次 COVID-19 危机中提出的伦理问题至关重要。在本文中,我们着眼于在 COVID-19 患者的检测和追踪中提出的问题。我们通过强调并扩展 Fineberg 提出的一种方法来做到这一点,该方法可以作为一种公共卫生方法。通过这种方式,我们强调了几个伦理问题。在检测方面,人们提出了这样的问题,即是否可以使用不太可靠的测试来提高检测能力或最大限度地减少对患者的伤害。另一个问题是应该进行多广泛的检测,以及选择性检测是否符合社会正义原则。从 COVID-19 中康复的患者可能具有一定程度的免疫力,但赋予某些“免疫特权”会引发伦理问题。各种追踪方法(移动应用程序或数据库和受过训练的追踪者)的使用引发了明显的社会正义和隐私问题。我们认为,始终坚持进行相称性检验至关重要,必须在其中寻求公平的平衡。