Programa de Pós-graduação em Bioquímica Toxicológica, Universidade Federal de Santa Maria, Santa Maria, RS, Brazil.
Programa de Pós-graduação em Zootecnia, Universidade do Estado de Santa Catarina (UDESC), Chapecó, SC, Brazil.
Microb Pathog. 2021 Jul;156:104936. doi: 10.1016/j.micpath.2021.104936. Epub 2021 May 2.
Motivated by conventional medicines' ineffectiveness and the appearance of bacterial resistance, homeopathic medicines are being increasingly demanded by the veterinary market. Dog feces contain high bacterial and pathogenic loads, which can cause diseases in animals and facilitate zoonotic transmission. Adequate animal immunity contributes to the elimination of potential pathogens. This work's objective was to evaluate the effects of using a homeopathic medication on blood cell counts, serum protein levels, and fecal bacterial counts in dogs. Two groups were used, each including five 19-month-old Beagle dogs. The homeopathic product Orgainfecto® was sprayed on the two daily meals in the treated group (T), at 0.5 mL/animal/day for 60 days; the group that did not receive the homeopathic was considered the control (C), who were fed only the vehicle used in the production of the homeopathic as a placebo. On days 1, 30, and 60, individual stool samples were collected for bacterial counts in the stool, blood samples for blood counts, and serum for biochemical tests. Total bacterial counts in feces were lower in group T on days 30 and 60 of the experiment, while total coliforms and E coli. were lower in this group on day 60. Total leukocyte counts were lower on day 60 in group T, unlike the neutrophil count, higher in group T on day 30, and eosinophils on day 60. However, the lymphocyte count was lower in group T on days 30 and 60. There was an increase in globulin and total protein in group T on day 60. We conclude that the tested homeopathic causes neutrophils and eosinophils' stimulation and increases globulins levels even with reduced lymphocytes. The daily consumption of homeopathic by dogs decreases the intestinal bacterial load, resulting in less environmental contamination and animal and human colibacillosis risks.
受传统医学无效性和细菌耐药性出现的影响，顺势疗法药物在兽医市场的需求日益增加。狗的粪便中含有大量的细菌和病原体，这些细菌和病原体可能导致动物患病，并促进人畜共患病的传播。适当的动物免疫力有助于消除潜在的病原体。本工作的目的是评估使用顺势疗法药物对犬血细胞计数、血清蛋白水平和粪便细菌计数的影响。使用了两组，每组包括五只 19 个月大的比格犬。在治疗组（T）中，将顺势疗法产品 Orgainfecto®每天喷在两餐食物上，每只动物 0.5 毫升/天，持续 60 天；未接受顺势疗法的组被认为是对照组（C），仅喂食用于生产顺势疗法的载体作为安慰剂。在第 1、30 和 60 天，分别收集个体粪便样本进行粪便细菌计数、血液样本进行血液计数和血清进行生化测试。实验组第 30 和 60 天粪便中的总细菌计数较低，而第 60 天总大肠菌群和大肠杆菌计数较低。实验组第 60 天的总白细胞计数较低，与中性粒细胞计数相反，实验组第 30 天的中性粒细胞计数较高，第 60 天的嗜酸性粒细胞计数较高。然而，实验组第 30 和 60 天的淋巴细胞计数较低。实验组第 60 天球蛋白和总蛋白增加。我们得出结论，测试的顺势疗法会刺激中性粒细胞和嗜酸性粒细胞，并增加球蛋白水平，即使淋巴细胞减少。狗每天摄入顺势疗法会降低肠道细菌负荷，从而降低环境污染和动物与人的大肠杆菌病风险。
