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冠状动脉慢血流现象的超声心动图和实验室检查结果:横断面研究和综述。

Echocardiographic and laboratory findings in coronary slow flow phenomenon: cross-sectional study and review.

机构信息

Cardiology Department, Medical Faculty, Urmia University of Medical Sciences, 17 Shahrivar St., 571478334, Urmia, Iran.

出版信息

BMC Cardiovasc Disord. 2021 May 5;21(1):230. doi: 10.1186/s12872-021-02044-z.

DOI:10.1186/s12872-021-02044-z
PMID:33952204
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8097949/
Abstract

BACKGROUND

Coronary sow-flow phenomenon (CSFP) is defined as slow passage of the contrast injected into the coronary arteries without distal obstruction of the vessel.

METHODS

The present study was a cross-sectional, descriptive-analytical study performed at the Seyed-al-Shohada Heart Center during 2018-2019. The eligible patients based on the inclusion and exclusion criteria were divided into the study group showing the CSFP and the control group with normal epicardial coronary arteries.

RESULTS

The study included 124 patients. 67.9% of the study group and 39.4% of the control group were male patients (p-value = 0.001), and the mean patient age was 52.18 ± 12.55 and 51.77 ± 10.36 years in the study and control groups, respectively (p-value = 0.18). The study group had a significantly higher BMI than the control group (p < 0.05) and also a higher prevalence of smoking and hypertension. The variables of ALC, Hct, Plt, MPV, RDW, Cr, triglyceride, TC, and LDL, were higher in the study group. Given the echocardiographic findings, the mean E wave was significantly lower in the study group, while the control group had a significantly higher GLS (p-value = 0.01). Also, left anterior descending artery was the most common artery involved with CSFP.

CONCLUSION

The CSFP was significantly more common in men, smokers, hypertensive patients, and patients with high BMI. Moreover, these patients had significantly higher platelet count, MPV, LDL, and FBS. Some other laboratory variables were also higher in these patients. Given the echocardiographic findings, mild diastolic dysfunction and low GLS were also observed in the study group.

摘要

背景

冠状动脉慢血流现象(CSFP)定义为对比剂注入冠状动脉后缓慢通过,而血管远端无阻塞。

方法

本研究为 2018 年至 2019 年在塞耶德-阿尔-舒哈达心脏中心进行的一项横断面描述性分析研究。根据纳入和排除标准,将符合条件的患者分为显示 CSFP 的研究组和正常心外膜冠状动脉的对照组。

结果

本研究共纳入 124 例患者。研究组中 67.9%和对照组中 39.4%为男性患者(p 值=0.001),研究组和对照组患者的平均年龄分别为 52.18±12.55 岁和 51.77±10.36 岁(p 值=0.18)。研究组的 BMI 显著高于对照组(p<0.05),且吸烟和高血压的患病率也较高。研究组的 ALC、Hct、Plt、MPV、RDW、Cr、甘油三酯、TC 和 LDL 等变量较高。根据超声心动图检查结果,研究组的平均 E 波明显较低,而对照组的 GLS 明显较高(p 值=0.01)。此外,左前降支是 CSFP 最常见的受累动脉。

结论

CSFP 在男性、吸烟者、高血压患者和 BMI 较高的患者中更为常见。此外,这些患者的血小板计数、MPV、LDL 和 FBS 明显较高。这些患者的其他一些实验室变量也较高。根据超声心动图检查结果,研究组还观察到轻度舒张功能障碍和低 GLS。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3cc/8097949/790686a2b36f/12872_2021_2044_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3cc/8097949/790686a2b36f/12872_2021_2044_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c3cc/8097949/790686a2b36f/12872_2021_2044_Fig1_HTML.jpg

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