Al Saad Mouna, Shehadeh Amin, Meqbil Jehad, Elubous Khaled, Qablawi Mohammed, Abu-Yaghi Nakhleh
Department of Special Surgery/Ophthalmology Division, School of Medicine, The University of Jordan, Amman, Jordan.
Clin Ophthalmol. 2021 Apr 28;15:1809-1812. doi: 10.2147/OPTH.S308585. eCollection 2021.
To determine the relationship between central corneal thickness (CCT), ganglionic cell-inner plexiform layer thickness and macular nerve fibre layer (RNFL) thickness as measured by optical coherence tomography in a cohort of healthy subjects.
Sixty healthy eyes from 60 subjects were included in this study. All subjects had a standard slit-lamp examination and optical coherence tomography. Central corneal thickness was measured using the Optopol spectral domain optical coherence tomography (SD OCT) machine (version 7.2.0). A linear mixed effects model was used to assess the relationship between central corneal thickness (CCT) and ganglionic cell-inner plexiform layer thickness and macular retinal nerve fibre layer thickness (RNFL).
Sixty healthy eyes from 60 subjects were included in this study. The average age was 41.8 years (±20.6 years). There were 22 males (37%) and 38 females (63%). The average central corneal thickness was 525.2 ± 35.1 µm (451-601) µm. The average macular retinal nerve fiber layer thickness was 28.9 ± 2.5 µm (23-38µm), and the average ganglionic cell-inner plexiform layer thickness was 88.6 ± 6.3 µm (75-110 µm). We found no statistically significant relationship between central corneal thickness and ganglionic cell-inner plexiform layer thickness (p=0.983) nor with macular RNFL (p =0.285).
In this cohort of healthy subjects, there was no statistically significant relationship between central corneal thickness and ganglionic cell-inner plexiform layer thickness or with macular retinal nerve fibre layer thickness.
在一组健康受试者中，通过光学相干断层扫描确定中央角膜厚度（CCT）、神经节细胞 - 内丛状层厚度与黄斑神经纤维层（RNFL）厚度之间的关系。
本研究纳入了60名受试者的60只健康眼睛。所有受试者均接受了标准的裂隙灯检查和光学相干断层扫描。使用Optopol光谱域光学相干断层扫描（SD OCT）机器（版本7.2.0）测量中央角膜厚度。采用线性混合效应模型评估中央角膜厚度（CCT）与神经节细胞 - 内丛状层厚度以及黄斑视网膜神经纤维层厚度（RNFL）之间的关系。
本研究纳入了60名受试者的60只健康眼睛。平均年龄为41.8岁（±20.6岁）。其中男性22名（37%），女性38名（63%）。平均中央角膜厚度为525.2±35.1µm（451 - 601）µm。平均黄斑视网膜神经纤维层厚度为28.9±2.5µm（23 - 38µm），平均神经节细胞 - 内丛状层厚度为88.6±6.3µm（从75至110µm）。我们发现中央角膜厚度与神经节细胞 - 内丛状层厚度之间无统计学显著关系（p = 0.983），与黄斑RNFL也无统计学显著关系（p = 0.285）。
在这组健康受试者中，中央角膜厚度与神经节细胞 - 内丛状层厚度或黄斑视网膜神经纤维层厚度之间无统计学显著关系。
