Department of Epidemiology and Biostatistics, School of Public Health, Jackson State University, Jackson, Mississippi, USA.
Sandra Rosenbaum School of Social Work, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Am J Hypertens. 2021 Sep 22;34(9):956-962. doi: 10.1093/ajh/hpab068.
In Mississippi, hypertension as a leading cause of death moved from 15th in 2000 to 11th in 2018, but research on temporal trends is limited. We examined temporal trends in hypertension-related mortality among Mississippi adults by age, sex, and race.
We extracted data on the number of deaths due to hypertension among adults aged 45 or older annually from 2000 to 2018 from Mississippi Vital Statistics. We used underlying cause-of-death codes from the International Classification of Diseases, Tenth Revision to identify hypertension deaths. We calculated the annual percentage change (trend segment) and average annual percentage change (AAPC) in age-adjusted hypertension death rates from 2000 to 2018 and examined differences in the AAPC by age, sex, and race.
From 2000 through 2018, the age-adjusted hypertension death rate increased annually by 3.0% (AAPC 3.0%, 95% confidence interval, 1.9%-4.0%) with 3 distinct time periods. There was an average annual increase in age-adjusted hypertension death rates for all subgroups, i.e., men, women, Blacks, Whites, White females, Black males, and White males. The highest magnitude of increase was among those aged 45-64 years (AAPC 6.0%), men (AAPC 4.5%), Whites (AAPC 3.5%), and White men (AAPC 6.2%) compared with other age groups, women, Blacks, and Black men, respectively.
For nearly 2 decades, there was an increase in age-adjusted hypertension death rates among Mississippi adults aged 45 years or older. Blood pressure lowering interventions that target hypertensive adults are needed.
在密西西比州，高血压作为主要死因的排名从 2000 年的第 15 位上升到 2018 年的第 11 位，但相关研究仍很有限。本研究旨在分析密西西比州成年人群高血压相关死亡率的时间趋势及其与年龄、性别和种族的关系。
我们从密西西比州生命统计数据库中提取了 2000 年至 2018 年 45 岁及以上成年人因高血压导致的死亡人数数据。我们使用国际疾病分类第十版的根本死因编码来识别高血压死亡病例。计算了 2000 年至 2018 年年龄校正后高血压死亡率的年变化百分比（趋势段）和平均年变化百分比（AAPC），并分析了年龄、性别和种族之间 AAPC 的差异。
2000 年至 2018 年，年龄校正后高血压死亡率每年增加 3.0%（AAPC 3.0%，95%置信区间 1.9%-4.0%），呈现 3 个不同时期。所有亚组（男性、女性、黑人、白人、白人女性、黑人男性和白人男性）的年龄校正后高血压死亡率均呈逐年上升趋势。45-64 岁人群（AAPC 6.0%）、男性（AAPC 4.5%）、白人（AAPC 3.5%）和白人男性（AAPC 6.2%）的增幅最大，而其他年龄组、女性、黑人以及黑人男性的增幅则较小。
近 20 年来，密西西比州 45 岁及以上成年人的年龄校正后高血压死亡率呈上升趋势。需要针对高血压成年人群开展降压干预措施。
