Department of Oral and Maxillofacial Surgery, King Abdulaziz University, Jeddah, Saudi Arabia.
Department of Oral and Maxillofacial Surgery, University of Florida, Gainesville, FL, 32603, USA.
Oral Maxillofac Surg. 2022 Mar;26(1):105-111. doi: 10.1007/s10006-021-00965-9. Epub 2021 May 5.
Dysgeusia and anosmia have been liked to COVID-19 infection. The aim of this study is to study the prevalence of dysgeusia and anosmia in COVID-19 patients treated at the University of Florida Health Center and establish the odds of having an olfactory and gustatory disorder with a confirmed COVID-19 infection.
This is a retrospective cross-sectional study utilizing the University of Florida Health Center patients' registry i2b2 platform to search for ICD 10 diagnoses of COVID-19 infection and taste and smell disturbances. We assessed the odds ratio for patients with dysgeusia and anosmia having a laboratory-confirmed COVID-19 infection using a logistic regression model adjusting for gender, race, age, and comorbidity conditions. P < 0.05 was deemed significant.
Out of 889 individuals that tested positive for COVID-19, 12.88% were diagnosed with taste and smell disturbances. The odds ratio for COVID-19 for people with dysgeusia and anosmia was 39.107. After adjusting for sex, age, and race, it was 41.9, 37, and 34.2, respectively.
Taste and smell disturbances in COVID-19 are not anecdotal. It is paramount that oral and maxillofacial surgeons include taste and smell disturbances in the history and physical examination as these symptoms are suspicious of active COVID-19 infection. Patients presenting with an olfactory and gustatory disorder should undergo further evaluations for COVID-19 infection and oral and maxillofacial surgeons should enhance the personal protective equipment used when treating these patients to prevent further spread of the infection and protect other healthcare members.
味觉障碍和嗅觉障碍与 COVID-19 感染有关。本研究旨在研究在佛罗里达大学健康中心接受治疗的 COVID-19 患者味觉障碍和嗅觉障碍的患病率，并确定嗅觉和味觉障碍与确诊 COVID-19 感染的几率。
这是一项回顾性横断面研究，利用佛罗里达大学健康中心患者的 i2b2 登记平台搜索 COVID-19 感染的 ICD-10 诊断和味觉及嗅觉障碍。我们使用逻辑回归模型评估味觉障碍和嗅觉障碍患者实验室确诊 COVID-19 感染的比值比，同时调整性别、种族、年龄和合并症状况。P<0.05 被认为具有统计学意义。
在 889 名 COVID-19 检测呈阳性的个体中，12.88%被诊断为味觉和嗅觉障碍。味觉和嗅觉障碍患者 COVID-19 的比值比为 39.107。调整性别、年龄和种族后，比值比分别为 41.9、37 和 34.2。
COVID-19 中的味觉和嗅觉障碍并非偶然。口腔颌面外科医生在病史和体检中应将味觉和嗅觉障碍纳入其中，因为这些症状可疑为活动性 COVID-19 感染。出现嗅觉和味觉障碍的患者应进一步进行 COVID-19 感染评估，口腔颌面外科医生在治疗这些患者时应增强个人防护设备的使用，以防止感染进一步传播并保护其他医护人员。
