Department of Otolaryngology-Head and Neck Surgery, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Department of Physiology and Biophysics, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Otolaryngol Head Neck Surg. 2020 Aug;163(2):302-306. doi: 10.1177/0194599820929957. Epub 2020 May 19.
Since the COVID-19 pandemic began, many individuals have noted acute loss of smell and/or taste, although not all patients with these symptoms are tested for COVID-19. To better characterize all patients with these rare symptoms, a national survey was created. Over 13 days in April 2020, a total of 220 people completed the survey in its entirety, representing a wide geographic distribution across the United States. Of the 220 respondents, 93 (42%) were diagnosed with COVID-19, and 127 (58%) were not. A total of 37.7% of respondents reported changes in smell/taste as the initial or sole presentation of their condition. Most but not all patients had other symptoms suggestive of COVID-19 at the time of chemosensory loss. Despite its inclusion as a major symptom of COVID-19 by the CDC (Centers for Disease Control and Prevention), respondents with additional CDC-defined symptoms associated with COVID-19 were statistically more likely to be tested/diagnosed than those without.
自 COVID-19 大流行开始以来，许多人都注意到嗅觉和/或味觉明显丧失，尽管并非所有出现这些症状的患者都接受了 COVID-19 检测。为了更好地描述所有出现这些罕见症状的患者，我们开展了一项全国性调查。2020 年 4 月的 13 天内，共有 220 人完整填写了调查问卷，代表了美国各地广泛的地域分布。在 220 名受访者中，93 人（42%）被诊断为 COVID-19，127 人（58%）未被诊断为 COVID-19。37.7%的受访者报告说，嗅觉/味觉改变是其病情的最初或唯一表现。大多数（但并非全部）患者在出现嗅觉丧失时已经出现其他提示 COVID-19 的症状。尽管嗅觉丧失被疾病预防控制中心（Centers for Disease Control and Prevention）列为 COVID-19 的主要症状之一，但与 COVID-19 相关的其他被疾病预防控制中心定义的症状的患者接受检测/诊断的可能性比没有这些症状的患者更高。
