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100 毫升水吞咽测试对头颈部癌症患者和健康受试者的可靠性。

Reliability of the 100 mL water swallow test in patients with head and neck cancer and healthy subjects.

机构信息

Department of Radiation Oncology, Imaging Division, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.

Department of Otolaryngology-Head and Neck Surgery and Cancer Center Amsterdam, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

出版信息

Head Neck. 2021 Aug;43(8):2468-2476. doi: 10.1002/hed.26723. Epub 2021 May 6.

Abstract

BACKGROUND

Dysphagia may occur in up to 44% of patients with head and neck cancer (HNC) treated with radiation therapy and up to 84% of patients treated with surgery. To test the extent of dysphagia, the 100 mL water swallow test (WST) was developed. In this study, reliability of the 100 mL WST was determined in patients with HNC and healthy subjects.

METHODS

Thirty-three patients and 40 healthy subjects performed the WST twice on the same day. To assess reliability, the intraclass correlation coefficient (ICC ), standard error of measurement, smallest detectable change, and limits of agreement were calculated.

RESULTS

Good to excellent correlations were found for patients with HNC (number of swallows; ICC = 0.923, duration; ICC = 0.893), and excellent correlations for healthy subjects (number of swallows; ICC = 0.950, duration; ICC = 0.916).

CONCLUSION

The 100 mL WST has a good to excellent reliability in patients with HNC and healthy subjects.

摘要

背景

接受放射治疗的头颈部癌症(HNC)患者中,多达 44%可能出现吞咽困难,接受手术治疗的患者中,多达 84%可能出现吞咽困难。为了测试吞咽困难的程度,开发了 100ml 水吞咽测试(WST)。在这项研究中,确定了 HNC 患者和健康受试者中 100ml WST 的可靠性。

方法

33 名患者和 40 名健康受试者在同一天进行了两次 WST。为了评估可靠性,计算了组内相关系数(ICC)、测量误差、最小可检测变化和一致性界限。

结果

对于 HNC 患者,发现了良好到极好的相关性(吞咽次数;ICC=0.923,持续时间;ICC=0.893),对于健康受试者,发现了极好的相关性(吞咽次数;ICC=0.950,持续时间;ICC=0.916)。

结论

100ml WST 在 HNC 患者和健康受试者中具有良好到极好的可靠性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/947f/9543915/428d69feac76/HED-43-2468-g002.jpg

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