Department of Physics and Electronics, Osaka Prefecture University Sakai, Osaka, 599-8531, Japan.
JST PRESTO, Kawaguchi, Saitama, 332-0012, Japan.
Adv Healthc Mater. 2021 Sep;10(17):e2100103. doi: 10.1002/adhm.202100103. Epub 2021 May 6.
A disorder in the thermoregulator center in a human body leads to some potential diseases such as fever and hyperthyroidism. To predict these diseases early, monitoring the health condition of the human body due to the influence of thermoregulation disorders is important. Although extensive works are performed on sweat-rate detection by constructing microfluidic channels, skin-moisture evaporation before sweating remains unknown. This work proposes a wireless and flexible sensor sheet to investigate the thermoregulatory responses of different people under cold stimulation and exercise by measuring the temperature and moisture variations on the finger skin. An integrated flexible sensor system consists of a ZnIn S nanosheet-based humidity sensor and carbon nanotube/SnO temperature sensor. The results exhibit distinct thermoregulation abilities of five volunteers. Interestingly, the sudden increase in finger moisture that results from the excitation by the sympathetic nerve is observed during the cold-stimulus test. Although further studies are required to predict the potential diseases resulted from thermoregulation disorders in human body, this study provides a possibility of continuous and real-time monitoring of thermoregulatory activities via skin moisture and temperature detection using a flexible sensor sheet.
人体体温调节中心紊乱会导致一些潜在疾病，如发烧和甲状腺功能亢进。为了尽早预测这些疾病，监测由于体温调节障碍对人体健康状况的影响很重要。虽然已经有大量的工作致力于通过构建微流道来检测排汗率，但排汗前的皮肤湿度蒸发仍不清楚。本工作提出了一种无线和灵活的传感器片，通过测量手指皮肤上的温度和湿度变化，研究不同人在冷刺激和运动下的体温调节反应。一个集成的柔性传感器系统包括基于 ZnIn S 纳米片的湿度传感器和碳纳米管/SnO 温度传感器。结果显示了五个志愿者不同的体温调节能力。有趣的是，在冷刺激测试中观察到，由于交感神经的刺激，手指湿度会突然增加。尽管还需要进一步的研究来预测人体体温调节障碍导致的潜在疾病，但本研究通过使用柔性传感器片检测皮肤湿度和温度，为连续实时监测体温调节活动提供了一种可能性。
