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用于空间分辨体温监测的皮肤贴合式银片装饰的聚(3,4-乙撑二氧噻吩):聚苯乙烯磺酸盐传感器阵列

Skin-Conformal Ag Flake-Decorated PEDOT:PSS Sensor Arrays for Spatially Resolved Body Temperature Monitoring.

作者信息

Hwang Chuljin, Choi Jun-Gyu, Pang Changhyun, Kim Min-Seok, Park Sungjun

机构信息

Department of Electrical and Computer Engineering, Ajou University, Suwon, 16499, Republic of Korea.

School of Chemical Engineering, Sungkyunkwan University (SKKU), Suwon, 16419, Republic of Korea.

出版信息

Small. 2025 Aug;21(32):e2412675. doi: 10.1002/smll.202412675. Epub 2025 May 27.

Abstract

Rapid and spatial temperature measurement on the skin is essential for detecting localized physiological anomalies, such as inflammation or circulatory issues, while providing insights into thermoregulation. Skin-conformal temperature sensors, with ultra-flexible designs, enable precise and comfortable measurements, supporting real-time monitoring, early diagnosis, and effective intervention. However, achieving rapid and spatial skin-conformal temperature sensor arrays that simultaneously maintain high sensitivity under extreme mechanical stresses remains a significant challenge. This work introduces a skin-conformal temperature sensor array based on a composite of poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) and Ag flakes, fabricated on a 2-µm-thick parylene-C substrate. A simple mixing process achieves uniform dispersion of Ag flakes, enhancing electrical conductivity to 2.04 kS cm. The sensor demonstrates a temperature coefficient of resistance of -2.02%/°C (30-50 °C), a resolution of 0.5 °C, and a rapid response time under 0.41 s per 5 °C change. It endures over 1000 cycles of 200% strain and performs reliably under 3 µm bending radii. Demonstrating high-resolution sensitivity and spatial temperature mapping through letter pattern recognition, the sensor shows promise for applications in body temperature monitoring, thermal imaging, and early diagnosis of temperature-related health conditions.

摘要

对皮肤进行快速且空间分辨的温度测量对于检测局部生理异常(如炎症或循环问题)至关重要,同时还能深入了解体温调节情况。具有超灵活设计的皮肤贴合式温度传感器能够实现精确且舒适的测量,支持实时监测、早期诊断和有效干预。然而,要实现快速且空间分辨的皮肤贴合式温度传感器阵列,同时在极端机械应力下保持高灵敏度,仍然是一项重大挑战。这项工作介绍了一种基于聚(3,4 - 乙撑二氧噻吩):聚(苯乙烯磺酸盐)(PEDOT:PSS)与银片复合材料的皮肤贴合式温度传感器阵列,该阵列制备在2微米厚的聚对二甲苯 - C衬底上。一个简单的混合过程实现了银片的均匀分散,将电导率提高到2.04 kS/cm。该传感器的电阻温度系数为 -2.02%/°C(30 - 50°C),分辨率为0.5°C,每5°C变化的快速响应时间在0.41秒以内。它能承受超过1000次200%应变的循环,并在3微米弯曲半径下可靠运行。通过字母图案识别展示了高分辨率灵敏度和空间温度映射,该传感器在体温监测、热成像以及与温度相关健康状况的早期诊断应用中显示出前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1bb/12366251/b77469efeed6/SMLL-21-2412675-g001.jpg

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