Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA, USA.
Genentech, Inc., South San Francisco, CA, USA.
J Diabetes Sci Technol. 2022 Sep;16(5):1183-1189. doi: 10.1177/19322968211008838. Epub 2021 May 6.
Continuous glucose monitoring (CGM) devices are used for evaluating real-time glucose levels to optimize diabetes management. There is limited information, however, on whether readings differ when a device is placed on the right versus the left arm. This study evaluated the mean difference in glucose levels between the right and left arm and the effect of unilateral arm exercise on this difference. The effect of an intermittent fasting diet on body fat percentage was also evaluated.
In a prospective trial, 46 adult volunteers self-selected into the intermittent fasting (IF; = 23) or free-living (FL; = 23) diet group and were randomized into a unilateral arm exercise group. Volunteers had CGM sensors placed simultaneously on both arms for 12-14 days.
The mean glucose level in the right arm was significantly higher than the left arm by 3.7 mg/dL ( < .001), and this result was unaffected by diet or arm exercise. Glucose levels were in euglycemic range for 75.2% of the time in the right arm and 67.5% in the left arm ( < .001). The change from baseline in body fat percentage between the IF and FL diet groups was not significant.
Measured glucose level and time in euglycemic range differ per placement of the CGM device, and the implications of this difference should be considered in clinical practice and research.
连续血糖监测（CGM）设备用于评估实时血糖水平，以优化糖尿病管理。然而，关于设备放置在右臂与左臂时读数是否存在差异的信息有限。本研究评估了右臂与左臂之间葡萄糖水平的平均差异，以及单侧手臂运动对这种差异的影响。还评估了间歇性禁食饮食对体脂百分比的影响。
在一项前瞻性试验中，46 名成年志愿者自行选择间歇性禁食（IF；n = 23）或自由生活（FL；n = 23）饮食组，并随机分为单侧手臂运动组。志愿者的双臂同时佩戴 CGM 传感器 12-14 天。
右臂的平均血糖水平明显高于左臂 3.7mg/dL（<0.001），且该结果不受饮食或手臂运动的影响。右臂的血糖水平在 75.2%的时间内处于正常血糖范围内，而左臂为 67.5%（<0.001）。IF 和 FL 饮食组之间体脂百分比的基线变化无显著差异。
CGM 设备的放置位置会影响测量的血糖水平和正常血糖范围内的时间，在临床实践和研究中应考虑这种差异的影响。
