London Bridge Hospital, UK.
Guy's and St Thomas' Hospital NHS Foundation Trust, UK.
Ann R Coll Surg Engl. 2021 Jun;103(6):395-403. doi: 10.1308/rcsann.2020.7072. Epub 2021 May 6.
Postoperative pulmonary complications and mortality rates during the COVID-19 pandemic have been higher than expected, leading to mass cancellation of elective operating in the UK. To minimise this, the Guy's and St Thomas' Hospital NHS Foundation Trust elective surgery hub and the executive team at London Bridge Hospital (LBH) created an elective operating framework at LBH, a COVID-19 minimal site, in which patients self-isolated for two weeks and proceeded with surgery only following a negative preoperative SARS-CoV-2 polymerase chain reaction swab. The aim was to determine the rates of rates of postoperative COVID-19 infection.
The collaboration involved three large hospital trusts, covering the geographic area of south-east London. All patients were referred to LBH for elective surgery. Patients were followed up by telephone interview at four weeks postoperatively.
Three hundred and ninety-eight patients from 13 surgical specialties were included in the analysis. The median age was 60 (IQR 29-71) years. Sixty-three per cent (252/398) were female. In total, 78.4% of patients had an American Society of Anesthesiologists grade of 1-2 and the average BMI was 27.2 (IQR 23.7-31.8) kg/m. Some 83.6% (336/402) were 'major' operations. The rate of COVID-19-related death in our cohort was 0.25% (1/398). Overall, there was a 1.26% (5/398) 30-day postoperative all-cause mortality rate. Seven patients (1.76%) reported COVID-19 symptoms, but none attended the emergency department or were readmitted to hospital as a result.
The risk of contracting COVID-19 in our elective operating framework was very low. We demonstrate that high-volume major surgery is safe, even at the peak of the pandemic, if patients are screened appropriately preoperatively.
在 COVID-19 大流行期间,术后肺部并发症和死亡率高于预期,导致英国大量取消择期手术。为了尽量减少这种情况,盖伊和圣托马斯医院 NHS 基金会信托基金的择期手术中心和伦敦桥医院(LBH)的执行团队在 LBH 创建了一个择期手术框架,LBH 是一个 COVID-19 低风险站点,患者在那里自我隔离两周,只有在术前 SARS-CoV-2 聚合酶链反应拭子检测结果为阴性后才进行手术。目的是确定术后 COVID-19 感染率。
该合作涉及三个大型医院信托基金,涵盖了东南伦敦的地理区域。所有患者均被转介至 LBH 进行择期手术。患者在术后四周通过电话访谈进行随访。
共有来自 13 个外科专业的 398 名患者纳入分析。中位年龄为 60(IQR 29-71)岁。63%(252/398)为女性。共有 78.4%的患者美国麻醉医师协会分级为 1-2 级,平均 BMI 为 27.2(IQR 23.7-31.8)kg/m。约 83.6%(336/402)为“主要”手术。本队列中 COVID-19 相关死亡的发生率为 0.25%(1/398)。总的来说,术后 30 天的全因死亡率为 1.26%(5/398)。有 7 名患者(1.76%)报告出现 COVID-19 症状,但均未前往急诊室或因此再次入院。
在我们的择期手术框架中,感染 COVID-19 的风险非常低。我们证明,如果患者术前得到适当的筛查,即使在大流行高峰期,也可以安全进行大容量的主要手术。