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The Conundrum of Pain, Opiate Use, and Delirium: Analgosedation or Analgesia-First Approach?

作者信息

Hayhurst Christina J, Hughes Christopher G, Pandharipande Pratik P

机构信息

Department of Anesthesiology Vanderbilt University Medical Center Nashville, Tennessee.

Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center Vanderbilt University Medical Center Nashville, Tennessee.

出版信息

Am J Respir Crit Care Med. 2021 Sep 1;204(5):502-503. doi: 10.1164/rccm.202104-0968ED.

DOI:10.1164/rccm.202104-0968ED
PMID:33956575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8491271/
Abstract
摘要

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本文引用的文献

1
Opioid Use Increases the Risk of Delirium in Critically Ill Adults Independently of Pain.阿片类药物的使用会增加危重症成人发生谵妄的风险，与疼痛无关。
Am J Respir Crit Care Med. 2021 Sep 1;204(5):566-572. doi: 10.1164/rccm.202010-3794OC.
2
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.右美托咪定或丙泊酚用于机械通气脓毒症患者镇静。
N Engl J Med. 2021 Apr 15;384(15):1424-1436. doi: 10.1056/NEJMoa2024922. Epub 2021 Feb 2.
3
Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults.用 ABCDEF 集束化方案关爱危重症患者：15000 多例成人患者的 ICU 解放协作研究结果。
Crit Care Med. 2019 Jan;47(1):3-14. doi: 10.1097/CCM.0000000000003482.
4
Clinical Practice Guidelines for the Prevention and Management of Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU.成人 ICU 患者疼痛、躁动/镇静、谵妄、活动减少、睡眠障碍预防与管理临床实践指南。
Crit Care Med. 2018 Sep;46(9):e825-e873. doi: 10.1097/CCM.0000000000003299.
5
Early intensive care sedation predicts long-term mortality in ventilated critically ill patients.早期重症监护镇静预测机械通气危重症患者的长期死亡率。
Am J Respir Crit Care Med. 2012 Oct 15;186(8):724-31. doi: 10.1164/rccm.201203-0522OC. Epub 2012 Aug 2.
6
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.右美托咪定对比咪达唑仑或丙泊酚用于机械通气时间延长患者的镇静：两项随机对照试验
JAMA. 2012 Mar 21;307(11):1151-60. doi: 10.1001/jama.2012.304.
7
Delirium duration and mortality in lightly sedated, mechanically ventilated intensive care patients.轻度镇静机械通气重症监护患者的谵妄持续时间与死亡率。
Crit Care Med. 2010 Dec;38(12):2311-8. doi: 10.1097/CCM.0b013e3181f85759.
8
Prevalence and risk factors for development of delirium in burn intensive care unit patients.烧伤重症监护病房患者谵妄发生的患病率及危险因素
J Burn Care Res. 2010 Sep-Oct;31(5):706-15. doi: 10.1097/BCR.0b013e3181eebee9.
9
Prevalence and risk factors for development of delirium in surgical and trauma intensive care unit patients.外科和创伤重症监护病房患者谵妄发生的患病率及危险因素。
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Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.劳拉西泮是重症监护病房患者发生谵妄的独立危险因素。
Anesthesiology. 2006 Jan;104(1):21-6. doi: 10.1097/00000542-200601000-00005.