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[一例脊髓脊膜膨出所致神经源性膀胱合并膀胱鳞状细胞癌病例]

[A Case of Bladder Squamous Cell Carcinoma with Neurogenic Bladder Caused by Myelomeningocele].

作者信息

Maesaka Fumisato, Momose Hitoshi, Nakahama Tomonori, Yamada Atsushi, Matsumoto Yoshihiro

机构信息

The Department of Urology, enpan Community Health-Care Organization Hoshigaoka Medical Center.

The Department of Urology, enpan Community Health-Care Organization Hoshigaoka Medical Center; The Department of Urology, Hirao Hospital.

出版信息

Hinyokika Kiyo. 2021 Mar;67(3):103-107. doi: 10.14989/ActaUrolJap_67_3_103.

Abstract

A 38-year-old woman with neurogenic bladder caused by myelomeningocele,who had been on clean intermittent self-catheterization for years,complained of gross hematuria. Computerized tomography, urinary cytology and cystoscopy failed to reveal causative lesions and the hematuria ceased spontaneously. Because gross hematuria recurred 2 years later,we examined the patient again and detected calcification of the urinary bladder. Mucosal lesions suspicious of bladder tumor were detected during the transurethral surgery for the calcified lesion,and we promptly performed biopsy. As a result,she was diagnosed with invasive bladder squamous cell carcinoma. Radical cystectomy and urinary diversion were performed and the histopathological diagnosis was pT3aN0. Adjuvant therapies were not performed. No recurrence has been observed for 36 months after the surgery.

摘要

一名38岁患有脊髓脊膜膨出所致神经源性膀胱的女性,多年来一直进行清洁间歇性自我导尿,主诉肉眼血尿。计算机断层扫描、尿液细胞学检查和膀胱镜检查均未发现病因性病变,且血尿自行停止。由于2年后再次出现肉眼血尿,我们再次对该患者进行检查,发现膀胱钙化。在针对钙化病变的经尿道手术中检测到可疑膀胱肿瘤的黏膜病变,我们立即进行了活检。结果,她被诊断为浸润性膀胱鳞状细胞癌。进行了根治性膀胱切除术和尿流改道,组织病理学诊断为pT3aN0。未进行辅助治疗。术后36个月未观察到复发。

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