Geraniotis E, Koff S A, Enrile B
Department of Surgery, Ohio State University College of Medicine, Columbus.
J Urol. 1988 Jan;139(1):85-6. doi: 10.1016/s0022-5347(17)42300-7.
To examine the hypothesis that the prophylactic use of clean intermittent catheterization can prevent urinary tract deterioration in infants and young children with myelomeningocele a prospective controlled study was performed on 24 patients. Preliminary results indicate that more than 50 per cent of the patients with bladder sphincter incoordination managed by self-voiding had urinary tract deterioration. In contrast, in only 10 per cent of the patients treated prophylactically with clean intermittent catheterization did deterioration occur. We conclude that when bladder sphincter incoordination is diagnosed in children with myelomeningocele they are at a high risk for the development of future urinary tract injury. The prophylactic use of clean intermittent catheterization can actually prevent this deterioration and its use in this manner is recommended.
为检验清洁间歇性导尿的预防性使用能否预防脊髓脊膜膨出婴幼儿的尿路恶化这一假设,对24例患者进行了一项前瞻性对照研究。初步结果表明,通过自主排尿管理膀胱括约肌不协调的患者中,超过50%出现了尿路恶化。相比之下,接受清洁间歇性导尿预防性治疗的患者中,只有10%出现了恶化。我们得出结论,当在脊髓脊膜膨出患儿中诊断出膀胱括约肌不协调时,他们未来发生尿路损伤的风险很高。清洁间歇性导尿的预防性使用实际上可以预防这种恶化,建议以这种方式使用。