Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI.
Diabetes Care. 2021 May;44(5):1108-1115. doi: 10.2337/dc20-0307. Epub 2021 May 6.
To simulate the long-term cost-effectiveness of a peer leader (PL)-led diabetes self-management support (DSMS) program following a structured community health worker (CHW)-led diabetes self-management education (DSME) program in reducing risks of complications in people with type 2 diabetes (T2D).
The trial randomized 222 Latino adults with T2D to ) enhanced usual care (EUC); ) a CHW-led, 6-month DSME program and 6 months of CHW-delivered monthly telephone outreach (CHW only); or ) a CHW-led, 6-month DSME program and 12 months of PL-delivered weekly group sessions with telephone outreach to those unable to attend (CHW PL). Empirical data from the trial and the validated Michigan Model for Diabetes were used to estimate cost and health outcomes over a 20-year time horizon from a health care sector perspective, discounting both costs and benefits at 3% annually. The primary outcome measure was the incremental cost-effectiveness ratio (ICER).
Over 20 years, the CHW + PL intervention had an ICER of $28,800 and $5,900 per quality-adjusted life-year (QALY) gained compared with the EUC and CHW-only interventions, respectively. The CHW-only intervention had an ICER of $430,600 per QALY gained compared with the EUC intervention. In sensitivity analyses, the results comparing the CHW + PL with EUC and CHW-only interventions were robust to changes in intervention effects and costs.
The CHW + PL-led DSME/DSMS intervention improved health and provided good value compared with the EUC intervention. The 6-month CHW-led DSME intervention without further postintervention CHW support was not cost effective in Latino adults with T2D.
模拟同伴领导(PL)主导的糖尿病自我管理支持(DSMS)计划在结构化社区卫生工作者(CHW)主导的糖尿病自我管理教育(DSME)计划之后,降低 2 型糖尿病(T2D)患者并发症风险的长期成本效益。
该试验将 222 名拉丁裔 T2D 成人随机分为)强化常规护理(EUC);)CHW 主导的 6 个月 DSME 计划和 6 个月 CHW 提供的每月电话随访(仅 CHW);或)CHW 主导的 6 个月 DSME 计划和 12 个月 PL 提供的每周小组会议,对无法参加的人进行电话随访(CHW+PL)。试验的实证数据和经过验证的密歇根糖尿病模型用于从医疗保健部门的角度估算 20 年时间内的成本和健康结果,对成本和效益按每年 3%进行贴现。主要结果衡量指标是增量成本效益比(ICER)。
在 20 年内,与 EUC 和 CHW 单一干预相比,CHW+PL 干预的 ICER 分别为每获得 1 个质量调整生命年(QALY)的 28800 美元和 5900 美元。CHW 单一干预的 ICER 为每获得 1 个 QALY 的 430600 美元,与 EUC 干预相比。在敏感性分析中,与 EUC 和 CHW 单一干预相比,CHW+PL 干预的结果对干预效果和成本的变化具有稳健性。
与 EUC 干预相比,CHW+PL 主导的 DSME/DSMS 干预改善了健康状况,并具有良好的价值。在没有进一步的 CHW 支持的情况下,6 个月的 CHW 主导的 DSME 干预在拉丁裔 T2D 成人中并不具有成本效益。