Center for Neural Science, New York University, New York, New York 10003
J Neurosci. 2021 Jun 9;41(23):4949-4953. doi: 10.1523/JNEUROSCI.0512-21.2021. Epub 2021 May 6.
Some of us fortunate enough to have published a paper in in its inaugural year (1981) have been asked to write a Progressions article addressing our views on the significance of the original work and how ideas about the topic of that work have evolved over the last 40 years. These questions cannot be effectively considered without placing them in the context of the incredible growth of the overall field of neuroscience over these last four decades. For openers, in 1981, the Nobel Prize was awarded to three neuroscience superstars: Roger Sperry, David Hubel, and Torsten Wiesel. Not a bad year to launch the With this as a backdrop, I divide this Progressions article into two parts. First, I discuss our original (1981) paper describing classical conditioning in , and place our results in the context of the state of the field at the time. Second, I fast forward to the present and consider some of remarkable progress in the broad field of learning and memory that has occurred in the last 40 years. Along the way, I also reflect briefly on some of the amazing advances, both technical and conceptual, that we in neuroscience have witnessed.
我们中的一些幸运儿在 1981 年创刊当年就发表了一篇论文，现在被要求写一篇进展文章，阐述我们对原始工作的重要性的看法，以及关于该工作主题的想法在过去 40 年中是如何演变的。如果不将这些问题置于过去四十年神经科学整体领域令人难以置信的发展背景下，就无法有效地考虑这些问题。首先，1981 年，诺贝尔奖授予了三位神经科学巨星：罗杰·斯佩里、大卫·休贝尔和托斯坦·威塞尔。这是一个很好的时机推出 。有了这个背景，我将这篇进展文章分为两部分。第一，我讨论了我们最初（1981 年）的论文，描述了 在 中的经典条件反射，并将我们的结果置于当时的领域状况。其次，我直接跳到现在，考虑在过去 40 年中，在广泛的学习和记忆领域中发生的一些显著进展。在这个过程中，我还简要地反思了我们神经科学界见证的一些令人惊叹的技术和概念上的进步。
