Crudo David F, Walsh Elizabeth T, Hunter Janel D
Pediatric Endocrinology, Wake Forest University School of Medicine, Winston-Salem, USA.
Cureus. 2021 Apr 3;13(4):e14273. doi: 10.7759/cureus.14273.
Diabetic ketoacidosis (DKA) and thyroid storm are serious complications of underlying disease states. Either condition can induce the other, and the co-occurrence of these conditions is uncommon. We present the case of an adolescent patient with type 1 diabetes and autoimmune hypothyroidism who developed recurrent concurrent DKA and thyroid storm twice in an eight-month period. The simultaneous development of DKA and thyroid storm is uncommon with only 28 cases previously reported. Co-presentation of these two life-threatening conditions occurs in people with either preexisting diabetes, thyroid disease, or both. The purported pathophysiology of how DKA and thyroid storm affect the other is discussed.
糖尿病酮症酸中毒（DKA）和甲状腺危象是基础疾病的严重并发症。这两种情况均可诱发对方，且它们同时出现的情况并不常见。我们报告了一例1型糖尿病和自身免疫性甲状腺功能减退的青少年患者，该患者在八个月内两次反复并发DKA和甲状腺危象。DKA和甲状腺危象同时发生的情况并不常见，此前仅报告过28例。这两种危及生命的情况同时出现于既往患有糖尿病、甲状腺疾病或两者皆有的患者中。本文讨论了DKA和甲状腺危象相互影响的假定病理生理学机制。
