Guo Meng-Ni, Jalil Anum, Liu Jie-Ying, Miao Ruo-Yu, Tran Tien Anh, Guan Jian
Department of Internal Medicine, AdventHealth Orlando, Orlando, FL 32804, United States.
Department of Pathology, AdventHealth Orlando, Orlando, FL 32804, United States.
World J Clin Oncol. 2021 Apr 24;12(4):282-289. doi: 10.5306/wjco.v12.i4.282.
Sarcomatoid carcinoma is a rare subtype of non-small-cell lung cancer, commonly associated with locally advanced disease, early metastasis, and poor prognosis. Tongue metastasis from lung cancer is a rare condition that may occur in advanced stage of the disease.
The patient was a 70-year-old female with a history of resected pulmonary sarcomatoid carcinoma (PSC) who presented with subacute tongue swelling, imparting the clinical impression of a lingual abscess. However, histologic examination of the partial glossectomy revealed a high-grade, poorly differentiated spindle and epithelioid carcinoma consistent with metastatic PSC.
Although uncommon, clinicians should be cognizant of the possibility of a metastatic process to the tongue mimicking a benign or inflammatory process. A high index of suspicion for metastatic disease should be maintained when tongue swelling is observed in patients with a known history of PSC.
肉瘤样癌是非小细胞肺癌的一种罕见亚型，通常与局部晚期疾病、早期转移及预后不良相关。肺癌转移至舌部是一种罕见情况，可能发生于疾病晚期。
该患者为一名70岁女性，有肺肉瘤样癌（PSC）切除病史，表现为亚急性舌部肿胀，临床印象为舌部脓肿。然而，部分舌切除术的组织学检查显示为高级别、低分化梭形和上皮样癌，符合转移性PSC。
尽管不常见，但临床医生应认识到舌部出现类似良性或炎症性病变的转移过程的可能性。对于有PSC已知病史且出现舌部肿胀的患者，应高度怀疑转移性疾病。
