Barber C, Eylan E
Zentralbl Bakteriol Orig A. 1977 Sep;239(1):46-50.
Agar-gel precipitations of proteins from S. paratyphi C, S. paratyphi B and S. typhimurium against homologous and heterologous antibacterial sera, prepared in rabbits, demonstrated a strong relatedness between these species belonging to different serogroups. The findings explain and substantiate previous experiments in which high cross-protections were obtained in groups of mice immunized with proteins from these species and subsequently infected with S. typhimurium or its "in vivo" related S. paratyphi B and S. paratyphi C.
用兔制备的抗甲型副伤寒沙门氏菌、乙型副伤寒沙门氏菌和鼠伤寒沙门氏菌的同源及异源抗菌血清对这些细菌的蛋白质进行琼脂凝胶沉淀试验,结果表明,这些属于不同血清群的细菌之间存在很强的相关性。这些发现解释并证实了先前的实验,即在一组用这些细菌的蛋白质免疫、随后感染鼠伤寒沙门氏菌或其“体内”相关菌乙型副伤寒沙门氏菌和甲型副伤寒沙门氏菌的小鼠中获得了高度交叉保护。