Kanerva L, Tupasela O, Jolanki R, Vaheri E, Estlander T, Keskinen H
Institute of Occupational Health, Helsinki, Finland.
Clin Allergy. 1988 May;18(3):245-52. doi: 10.1111/j.1365-2222.1988.tb02866.x.
Three cases of allergic rhinitis from a vegetable gum, guar gum, have been detected. Two subjects were exposed to fine guar gum powder (Emco Gum 563, Meyhall Chemical AG, Switzerland), an insulator in rubber cables, when opening cables in a power cable laboratory. After 1-2 years' exposure the patients developed rhinitis. Scratch-chamber tests, nasal provocation tests, nasal eosinophilia and a RAST test proved their allergy. A third subject developed allergic rhinitis from another guar gum product (Meyproid 5306, Meyhall Chemical AG) after 2 years' exposure in a paper factory. A positive skin test and nasal provocation test confirmed the diagnosis. A fourth case of possible allergy to guar gum after exposure to Meyproid 5306 in a paper factory is also presented. No final diagnosis was reached in this case (in 1974). The present subjects, only one of whom was atopic, developed allergy within 2 years, although their exposure to guar gum was not especially heavy. Therefore, when handling guar, adequate ventilation facilities should be provided and protective clothing, including a respiratory mask, should be worn.
已发现3例由植物胶瓜尔胶引起的变应性鼻炎。两名受试者在电力电缆实验室打开电缆时，接触到精细瓜尔胶粉末（瑞士梅哈尔化学公司的Emco Gum 563，橡胶电缆中的一种绝缘体）。接触1至2年后，患者出现鼻炎。划痕试验、鼻激发试验、鼻嗜酸性粒细胞增多及放射性变应原吸附试验证实了他们的过敏反应。第三名受试者在造纸厂接触另一种瓜尔胶产品（瑞士梅哈尔化学公司的Meyproid 5306）2年后出现变应性鼻炎。阳性皮肤试验和鼻激发试验确诊了该病。本文还介绍了造纸厂一名受试者接触Meyproid 5306后可能对瓜尔胶过敏的第四例病例。该病例（1974年）未得出最终诊断。目前这些受试者中只有一人是特应性体质，尽管他们接触瓜尔胶的程度并不特别严重，但在2年内就出现了过敏反应。因此，在处理瓜尔胶时，应提供足够的通风设施，并应穿戴包括呼吸面罩在内的防护服。
