Nuti R, Righi G, Martini G, Turchetti V, Lepore C, Doretti V
Institute of Clinical Medicine, University of Siena, Italy.
Clin Exp Rheumatol. 1988 Jan-Mar;6(1):47-51.
Dual-photon absorptiometry of total body (153 Gd with photopeaks at 44 and 100 keV) enables bone mineral content of the entire skeleton and its major anatomical areas to be quantitated. Total body bone mineral (TBBM), total body density (TBD), bone mineral content and bone density of spine and lumbar-spine were measured in 97 women with post-menopausal osteoporosis, 33 females with spondyloarthrosis and in 19 females with spondyloarthrosis associated with osteoporosis. Seventy-nine females of similar age made up the normal control group. TBBM and TBD proved to be significantly lower in post-menopausal osteoporotic women compared to age-matched normal females: bone loss was particularly evident in spine measurements. In spondyloarthrosis patients TBBM and TBD fell within the normal range and both spine bone density and spine bone mineral did not differ from normals. TBD, TBBM, spine density and spine mineral in females with disuse osteoporosis associated with spondyloarthrosis were significantly lower in comparison with normals and higher with respect to post-menopausal osteoporotic women. Total body absorptiometry represents a valuable method in the differential diagnosis of post-menopausal osteoporosis, spondyloarthrosis and the disuse osteoporosis associated with spondyloarthrosis.
全身双能光子吸收测定法（使用153钆，其光电峰位于44keV和100keV）能够对整个骨骼及其主要解剖区域的骨矿物质含量进行定量分析。对97名绝经后骨质疏松症女性、33名患有脊椎关节病的女性以及19名患有与骨质疏松症相关的脊椎关节病的女性，测量了全身骨矿物质（TBBM）、全身密度（TBD）、脊柱和腰椎的骨矿物质含量及骨密度。79名年龄相仿的女性组成了正常对照组。结果证明，绝经后骨质疏松症女性的TBBM和TBD显著低于年龄匹配的正常女性：在脊柱测量中骨量流失尤为明显。在脊椎关节病患者中，TBBM和TBD处于正常范围，脊柱骨密度和脊柱骨矿物质与正常人无差异。与脊椎关节病相关的废用性骨质疏松症女性的TBD、TBBM、脊柱密度和脊柱矿物质与正常人相比显著降低，与绝经后骨质疏松症女性相比则更高。全身吸收测定法是绝经后骨质疏松症、脊椎关节病以及与脊椎关节病相关的废用性骨质疏松症鉴别诊断中的一种有价值的方法。
