Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Azienda Ospedaliero Universitaria di Cagliari, Cagliari, Italy.
Trials. 2021 May 7;22(1):331. doi: 10.1186/s13063-021-05278-6.
Aging is marked by a progressive rise in chronic diseases with an impact on social and healthcare costs. Physical activity (PA) may soothe the inconveniences related to chronic diseases, has positive effects on the quality of life and biological rhythms, and can prevent the decline in motor functions and the consequent falls, which are associated with early death and disability in older adults.
We randomized 120 over-65 males and females into groups of similar size and timing and will give each either moderate physical activity or cultural and recreational activities. Being younger than 65 years, inability to participate in physical activity for any medical reason, and involvement in a massive program of physical exercise are the exclusion criteria. The primary outcome measures are: quality of life, walking speed, and postural sway. Participants are tested at baseline, post-treatment, and 6-month (24 weeks) and 12-month (48 weeks) follow-ups.
This study aims at improving the quality of life, wellness, and cognitive functioning in the elderly through a low-cost affordable program of moderate physical activity. Given the growing aging of the world population and the social and economic burden of disability in the elderly, our results might have a major impact on future practices.
ClinicalTrials.gov NCT03858114 . Registered on 28 February 2019.
衰老的标志是慢性病的发病率逐渐上升，这对社会和医疗保健成本都有影响。身体活动（PA）可以缓解慢性病带来的不便，对生活质量和生物节律有积极影响，还可以预防运动功能下降和随之而来的跌倒，这与老年人的早逝和残疾有关。
我们将 120 名 65 岁以上的男性和女性随机分为两组，每组的大小和时间相似，并将对他们分别进行中等强度的身体活动或文化和娱乐活动。年龄小于 65 岁、因任何医学原因无法参加身体活动以及参与大规模身体锻炼计划的人都被排除在外。主要的结局指标是：生活质量、步行速度和姿势摆动。参与者在基线、治疗后以及 6 个月（24 周）和 12 个月（48 周）的随访中接受测试。
本研究旨在通过一个负担得起的中等强度身体活动的低成本方案来提高老年人的生活质量、健康和认知功能。考虑到世界人口老龄化的增长以及老年人残疾的社会和经济负担，我们的研究结果可能会对未来的实践产生重大影响。
ClinicalTrials.gov NCT03858114，注册于 2019 年 2 月 28 日。
