Department of Physics, University of Guelph, 50 Stone Road East, Guelph, Ontario, Canada.
Iranian Light Source Facility, Institute for Research in Fundamental Sciences (IPM), Tehran, Iran.
Appl Radiat Isot. 2021 Aug;174:109731. doi: 10.1016/j.apradiso.2021.109731. Epub 2021 Apr 24.
Improving detection efficiency in small animal PET scanners without degrading spatial resolution is one of the main problems of these scanners. Commercial small animal PET scanners use different methods to achieve desirable levels of sensitivity and spatial resolution. GE Healthcare eXplore VISTA PET scanner uses double layer (LYSO-GSO) depth-of-interaction (DOI) capable cuboid detector modules. In this work, the design of GE Healthcare eXplore VISTA PET scanner is improved using tapered detector geometry instead of cuboid geometry. Using tapered detector geometry, the gaps between adjacent modules are filled and the sensitive volume has increased about 11.5%. The new designed PET scanner sensitivity and spatial resolution are studied for different crystal layer configurations (LYSO-GSO and GSO-LYSO with different thicknesses). As expected, average sensitivity over FOV is improved. Spatial resolution is slightly degraded but it is still uniform over FOV.
提高小动物 PET 扫描仪的探测效率而不降低空间分辨率是这些扫描仪的主要问题之一。商业小动物 PET 扫描仪使用不同的方法来达到理想的灵敏度和空间分辨率水平。GE Healthcare eXplore VISTA PET 扫描仪使用双层（LYSO-GSO）深度感应（DOI）能力的正方体探测器模块。在这项工作中，使用锥形探测器几何形状代替正方体几何形状来改进 GE Healthcare eXplore VISTA PET 扫描仪的设计。使用锥形探测器几何形状，相邻模块之间的间隙被填充，灵敏体积增加了约 11.5%。研究了不同晶体层配置（LYSO-GSO 和 GSO-LYSO 具有不同的厚度）下新型设计的 PET 扫描仪的灵敏度和空间分辨率。正如预期的那样，FOV 上的平均灵敏度得到了提高。空间分辨率略有下降，但在整个 FOV 上仍然均匀。
